SCHEMBL1003239

SCHEMBL1003239

CCCCCCNC(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 1.00
L3MBTL1 Q9Y468 1/20 0.73
HDAC3 O15379 6/20 0.70
HDAC4 P56524 3/20 0.70
HDAC1 Q13547 3/20 0.70
HDAC7 Q8WUI4 3/20 0.70
HDAC2 Q92769 3/20 0.70
HDAC10 Q969S8 3/20 0.70
HDAC11 Q96DB2 3/20 0.70
HDAC8 Q9BY41 3/20 0.70
HDAC6 Q9UBN7 3/20 0.70
HDAC9 Q9UKV0 3/20 0.70
HDAC5 Q9UQL6 3/20 0.70
SMN1; SMN2 Q16637 1/20 0.67
MLYCD O95822 1/20 0.65
DRD2 P14416 1/20 0.63
DRD4 P21917 1/20 0.63
DRD3 P35462 1/20 0.63
CA2 P00918 1/20 0.63
NPC1 O15118 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL587375 1.00 NAAA (1.00) NAAAL3MBTL1HDAC3HDAC4HDAC1
SCHEMBL29280581 1.00 NAAA (1.00) NAAAL3MBTL1HDAC3HDAC4HDAC1
SCHEMBL20216434 1.00 NAAA (1.00) NAAAL3MBTL1HDAC3HDAC4HDAC1
SCHEMBL8204741 1.00 NAAA (1.00) NAAAL3MBTL1HDAC3HDAC4HDAC1
SCHEMBL28927370 1.00 NAAA (1.00) NAAAL3MBTL1HDAC3HDAC4HDAC1
SCHEMBL1002305 1.00 NAAA (1.00) NAAAL3MBTL1HDAC3HDAC4HDAC1
SCHEMBL1002638 1.00 NAAA (1.00) NAAAL3MBTL1HDAC3HDAC4HDAC1
SCHEMBL1004555 1.00 NAAA (1.00) NAAAL3MBTL1HDAC3HDAC4HDAC1
SCHEMBL421014 1.00 NAAA (1.00) NAAAL3MBTL1HDAC3HDAC4HDAC1
SCHEMBL1002753 1.00 NAAA (1.00) NAAAL3MBTL1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107619950-A A kind of extracts composition, extraction system and its application 中国科学院上海有机化学研究所 2018-01-23 CN claimed
US-20240308989-A1 PYRAN DERIVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS ORION CORP (FI) 2024-09-19 US disclosed
US-12030871-B2 Pyran dervatives as CYP11A1 (cytochrome P450 monooxygenase 11A1) inhibitors ORION CORPORATION (FI) 2024-07-09 US disclosed
EP-4345091-A1 BENZOIC ACID DERIVATIVES, METHODS AND USES THEREOF Faculdade de Farmácia da Universidade de Lisboa (PT) 2024-04-03 EP disclosed
US-20230372915-A1 MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-11-23 US disclosed
US-20230372915-A1 MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-11-23 US disclosed
US-11793895-B2 Residualizing linkers and uses thereof CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION 2023-10-24 US disclosed
US-11731116-B2 Manganese based complexes and uses thereof for homogeneous catalysis YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-08-22 US disclosed
US-11731116-B2 Manganese based complexes and uses thereof for homogeneous catalysis YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-08-22 US disclosed
CN-109305949-B Monomer, polymer, compensation film, optical film and display device 三星电子株式会社 2023-08-15 CN disclosed
US-5864043-A CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST KARL THOMAE GMBH (DE) 1999-01-26 US disclosed
CN-1139925-A 'Delta' 12,13-iso-taxol analogs, antineoplastic use and pharmaceutical compositions containing them UPJOHN CO (US) 1997-01-08 CN disclosed
EP-0743304-A1 4-(Arylaminomethylene)-2,4-dihydro-pyrazol-3-ones MERCK PATENT GmbH (DE) 1996-11-20 EP disclosed
US-5541229-A ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1996-07-30 US disclosed
US-5223384-A Multilayer; paper support, subbing and photosensitive layer KONICA CORPORATION (JP) 1993-06-29 US disclosed
EP-0256820-B1 THERMAL DEVELOPING LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1992-07-29 EP disclosed
US-5032499-A High density, stability KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1991-07-16 US disclosed
US-4410530-A CARDIO-SELECTIVE B-RECEPTOR BLOCKING AGENTS AND STIMULANTS CIBA-GEIGY CORPORATION (US) 1983-10-18 US disclosed
US-4195090-A ADRENERGIC BLOCKING AGENTS CIBA-GEIGY CORPORATION (US) 1980-03-25 US disclosed
US-4115575-A CARDIOVASCULAR DISORDERS CIBA-GEIGY CORPORATION (US) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372915-A1 MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS ADH1C, OTC, MLEC NAAA 10/4885L3MBTL1 3312/4885HDAC3 1613/4885
US-11793895-B2 Residualizing linkers and uses thereof CD44, CD47, MTCL3 NAAA 745/4885L3MBTL1 1047/4885HDAC3 1018/4885
US-12030871-B2 Pyran dervatives as CYP11A1 (cytochrome P450 monooxygenase 11A1) inhibitors CYP11B1, CYP11B2, CYP4A11 NAAA 4286/4885L3MBTL1 1679/4885HDAC3 2116/4885
US-20240308989-A1 PYRAN DERIVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS CYP11B1, CYP11B2, CYP4A11 NAAA 4302/4885L3MBTL1 1781/4885HDAC3 1661/4885
US-11731116-B2 Manganese based complexes and uses thereof for homogeneous catalysis ADH1C, OTC, ADH5 NAAA 19/4885L3MBTL1 2926/4885HDAC3 1408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.