Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP1CA | P62136 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14998441 | 0.85 | ALDH1A1 (0.47) | PPP1CAKMT2AL3MBTL1MAPTNPSR1 | |
| SCHEMBL14998263 | 0.85 | TEAD1 (0.45) | PPP1CAKMT2AL3MBTL1MAPTNPSR1 | |
| SCHEMBL15003085 | 0.83 | ALDH1A1 (0.42) | PPP1CAKMT2AL3MBTL1MAPTNPSR1 | |
| SCHEMBL14998310 | 0.81 | KMT2A (0.46) | PPP1CAKMT2AL3MBTL1MAPTNPSR1 | |
| SCHEMBL14998507 | 0.79 | USP2 (0.47) | KMT2AL3MBTL1MAPTALDH1A1RAB9A | |
| SCHEMBL14998244 | 0.76 | CYP2C9 (0.54) | KMT2AL3MBTL1MAPTNPSR1ALDH1A1 | |
| SCHEMBL10036994 | 0.75 | MAPT (0.51) | MAPTTEAD1ALDH1A1RAB9AGAA | |
| SCHEMBL14998484 | 0.74 | PTGER4 (0.46) | KMT2AL3MBTL1NPSR1ALDH1A1RAB9A | |
| SCHEMBL10037133 | 0.72 | MAPT (0.45) | KMT2AMAPTALDH1A1POLB | |
| SCHEMBL10036988 | 0.72 | KDM4E (0.54) | KMT2AL3MBTL1MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2599774-B1 | CONDENSED PYRIDINE COMPOUNDS AS CB2 CANNABINOID RECEPTOR LIGANDS | ASTELLAS PHARMA INC (JP) | 2016-07-06 | — | — | EP | disclosed |
| US-8791106-B2 | Fused ring pyridine compound | ASTELLAS PHARMA INC. (JP) | 2014-07-29 | — | — | US | disclosed |
| US-20130143874-A1 | FUSED RING PYRIDINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2013-06-06 | — | — | US | disclosed |
| EP-2599774-A1 | CONDENSED RING PYRIDINE COMPOUND | Astellas Pharma Inc. (JP) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012014963-A1 | CONDENSED RING PYRIDINE COMPOUND | アステラス製薬株式会社 (JP) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143874-A1 | FUSED RING PYRIDINE COMPOUND | CNR2, CNR1, TRPV1 | PPP1CA 3811/4885KMT2A 1941/4885L3MBTL1 4685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.