Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10037279 | 1.00 | GRIK1 (0.32) | GRIK1ALDH1A1MAPTPTGS1SLC7A5 | |
| Glycine SCHEMBL28524251 | 0.91 | GLRA1 (0.43) | GRIK1ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL10110827 | 0.80 | DPP7 (0.40) | GRIK1DPP4DPP9DPP7GSR | |
| SCHEMBL12680193 | 0.80 | DPP7 (0.40) | GRIK1DPP4DPP9DPP7GSR | |
| SCHEMBL18159724 | 0.80 | DPP7 (0.40) | GRIK1DPP4DPP9DPP7GSR | |
| SCHEMBL24667723 | 0.79 | SLC1A2 (0.38) | GRIK1ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL17085295 | 0.79 | SLC1A1 (0.34) | GRIK1ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL15745571 | 0.79 | SLC1A1 (0.34) | GRIK1ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL17789294 | 0.79 | SLC1A1 (0.34) | GRIK1ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL17637587 | 0.79 | SLC1A2 (0.38) | GRIK1ALDH1A1MAPTPTGS1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | LSS, ABCG2, SELL | GRIK1 1932/4885ALDH1A1 533/4885MAPT 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.