SCHEMBL15745571

SCHEMBL15745571

CC(C)(C)C(=O)[C@@H](N)CO

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 1/20 0.34
PRKCA P17252 1/20 0.33
GRIK1 P39086 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC7A5 Q01650 1/20 0.32
SPHK1 Q9NYA1 2/20 0.31
GLS O94925 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17789294 1.00 SLC1A1 (0.34) SLC1A1PRKCAGRIK1ALDH1A1MAPT
SCHEMBL17085295 1.00 SLC1A1 (0.34) SLC1A1PRKCAGRIK1ALDH1A1MAPT
SCHEMBL8974968 0.80 SLC1A1 (0.32) SLC1A1GRIK1ALDH1A1MAPTPTGS1
SCHEMBL12420355 0.80 ALDH1A1 (0.40) GRIK1ALDH1A1MAPTPTGS1SLC7A5
SCHEMBL10001204 0.80 GABRP (0.34) SLC1A1GRIK1ALDH1A1MAPTPTGS1
SCHEMBL24667723 0.79 SLC1A2 (0.38) SLC1A1GRIK1ALDH1A1MAPTPTGS1
SCHEMBL10037279 0.79 GRIK1 (0.32) GRIK1ALDH1A1MAPTPTGS1SLC7A5
SCHEMBL10037276 0.79 GRIK1 (0.32) GRIK1ALDH1A1MAPTPTGS1SLC7A5
SCHEMBL17637587 0.79 SLC1A2 (0.38) SLC1A1GRIK1ALDH1A1MAPTPTGS1
SCHEMBL17789273 0.79 SLC1A2 (0.38) SLC1A1GRIK1ALDH1A1MAPTPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-12000846-B2 Click-mass spectrometry of alkyne-labeled compounds RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAET BONN (DE) 2024-06-04 US disclosed
US-11891457-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-06 US disclosed
US-20230348493-A1 COMPOUND FOR ADJUSTING ACTIVITY OF NMDA RECEPTOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF BEIJING GREATWAY PHARMACEUTICAL TECHNOLOGY CO. LTD. (CN) 2023-11-02 US disclosed
US-20230348493-A1 COMPOUND FOR ADJUSTING ACTIVITY OF NMDA RECEPTOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF BEIJING GREATWAY PHARMACEUTICAL TECHNOLOGY CO. LTD. (CN) 2023-11-02 US disclosed
EP-4137496-A1 COMPOUND FOR ADJUSTING ACTIVITY OF NMDA RECEPTOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Beijing Greatway Pharmaceutical Technology Co., Ltd. (CN) 2023-02-22 EP disclosed
US-20230023559-A1 ARYLMETHYLENE HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS D. E. SHAW RESEARCH, LLC (US) 2023-01-26 US disclosed
US-9381200-B2 Nitrogen containing compounds WOCKHARDT LIMITED (IN) 2016-07-05 US disclosed
US-20150328201-A1 NITROGEN CONTAINING COMPOUNDS WOCKHARDT LIMITED (IN) 2015-11-19 US disclosed
US-9132133-B2 Nitrogen containing compounds WOCKHARDT LTD. (IN) 2015-09-15 US disclosed
US-20150174133-A1 NITROGEN CONTAINING COMPOUNDS WOCKHARDT LIMITED (IN) 2015-06-25 US disclosed
US-8987297-B2 Nitrogen containing compounds WOCKHARDT LTD. (IN) 2015-03-24 US disclosed
US-20150005285-A1 Nitrogen containing compounds WOCKHARDT LIMITED (IN) 2015-01-01 US disclosed
US-8853197-B1 Nitrogen containing compounds WOCKHARDT LTD. (IN) 2014-10-07 US disclosed
US-20140275018-A1 NITROGEN CONTAINING COMPOUNDS WOCKHARDT LIMITED (IN) 2014-09-18 US disclosed
US-8822450-B2 1,6-diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections WOCKHARDT LTD. (IN) 2014-09-02 US disclosed
US-20140148431-A1 1,6- Diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections WOCKHARDT LIMITED (IN) 2014-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348493-A1 COMPOUND FOR ADJUSTING ACTIVITY OF NMDA RECEPTOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF GRIN1, GRIN3A, GRIN2C SLC1A1 62/4885PRKCA 1047/4885GRIK1 11/4885
US-20150174133-A1 NITROGEN CONTAINING COMPOUNDS NOS2, NOS1, NCF1 SLC1A1 661/4885PRKCA 4761/4885GRIK1 4337/4885
US-11891457-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R SLC1A1 3882/4885PRKCA 584/4885GRIK1 1341/4885
US-20150005285-A1 Nitrogen containing compounds NOS2, NOS1, NCF1 SLC1A1 661/4885PRKCA 4761/4885GRIK1 4337/4885
US-20140148431-A1 1,6- Diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections ODC1, AOC1, CASP7 SLC1A1 2866/4885PRKCA 4014/4885GRIK1 2804/4885
US-20150328201-A1 NITROGEN CONTAINING COMPOUNDS NOS2, NOS1, NCF1 SLC1A1 661/4885PRKCA 4761/4885GRIK1 4337/4885
US-20230023559-A1 ARYLMETHYLENE HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS KCNJ2, KCNA3, KCNH3 SLC1A1 998/4885PRKCA 2080/4885GRIK1 118/4885
US-20140275018-A1 NITROGEN CONTAINING COMPOUNDS NOS2, NOS1, NCF1 SLC1A1 661/4885PRKCA 4761/4885GRIK1 4337/4885
US-12000846-B2 Click-mass spectrometry of alkyne-labeled compounds KIT, ACSL4, ACSL6 SLC1A1 1279/4885PRKCA 1889/4885GRIK1 910/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R SLC1A1 3882/4885PRKCA 584/4885GRIK1 1341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.