SCHEMBL17637587

SCHEMBL17637587

CCC(N)C(=O)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 4/20 0.38
SLC1A1 P43005 4/20 0.38
SLC1A3 P43003 3/20 0.38
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
LAP3 P28838 1/20 0.33
GRIK1 P39086 5/20 0.32
GRIK2 Q13002 3/20 0.32
DPP4 P27487 3/20 0.32
DPP8 Q6V1X1 2/20 0.32
DPP9 Q86TI2 2/20 0.32
DPP7 Q9UHL4 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC7A5 Q01650 1/20 0.32
TSHR P16473 1/20 0.32
FAP Q12884 1/20 0.31
GCLC P48506 1/20 0.31
GRIA4 P48058 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24667723 1.00 SLC1A2 (0.38) SLC1A2SLC1A1SLC1A3CA1CA2
SCHEMBL17789273 1.00 SLC1A2 (0.38) SLC1A2SLC1A1SLC1A3CA1CA2
SCHEMBL16602076 0.80 SLC1A2 (0.42) SLC1A2SLC1A1SLC1A3CA1CA2
SCHEMBL23376611 0.80 SLC1A2 (0.42) SLC1A2SLC1A1SLC1A3CA1CA2
SCHEMBL17789275 0.80 SLC1A2 (0.42) SLC1A2SLC1A1SLC1A3CA1CA2
SCHEMBL17789294 0.79 SLC1A1 (0.34) SLC1A1GRIK1ALDH1A1MAPTPTGS1
SCHEMBL15745571 0.79 SLC1A1 (0.34) SLC1A1GRIK1ALDH1A1MAPTPTGS1
SCHEMBL10037279 0.79 GRIK1 (0.32) GRIK1DPP4DPP9DPP7ALDH1A1
SCHEMBL17085295 0.79 SLC1A1 (0.34) SLC1A1GRIK1ALDH1A1MAPTPTGS1
SCHEMBL10037276 0.79 GRIK1 (0.32) GRIK1DPP4DPP9DPP7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11529422-B2 Polymer linkers and their uses NOVACYTE THERAPEUTICS COMPANY., LTD (CN) 2022-12-20 US disclosed
US-20200155693-A1 POLYMER LINKERS AND THEIR USES NOVACYTE, INC. (US) 2020-05-21 US disclosed
US-20190083634-A1 POLYMER LINKERS AND THEIR USES NOVACYTE, INC. (US) 2019-03-21 US disclosed
US-20170045522-A1 FLUORESCENT MOLECULAR SENSOR FOR TARGETING CHANGES IN PROTEIN SURFACES, AND METHODS OF USE THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2017-02-16 US disclosed
US-20160089446-A1 Modified Hydrogels ASCENDIS PHARMA A/S (DK) 2016-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160089446-A1 Modified Hydrogels CD44, DNPH1, PHYKPL SLC1A2 2667/4885SLC1A1 2254/4885SLC1A3 3010/4885
US-11529422-B2 Polymer linkers and their uses PHF2, PHF8, PAICS SLC1A2 2112/4885SLC1A1 1066/4885SLC1A3 1241/4885
US-20190083634-A1 POLYMER LINKERS AND THEIR USES PHF2, PHF8, PAICS SLC1A2 2265/4885SLC1A1 1069/4885SLC1A3 1326/4885
US-20200155693-A1 POLYMER LINKERS AND THEIR USES PHF2, PHF8, PAICS SLC1A2 2112/4885SLC1A1 1066/4885SLC1A3 1241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.