SCHEMBL1003750

SCHEMBL1003750

C[CH]C(C)C(C)CCCC

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.36
TSHR P16473 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
OPRM1 P35372 1/20 0.35
ALDH1A1 P00352 3/20 0.32
TDP1 Q9NUW8 1/20 0.32
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31
ADH7 P40394 1/20 0.31
CYP3A4 P08684 1/20 0.31
FDPS P14324 1/20 0.31
LMNA P02545 1/20 0.30
CA2 P00918 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101539 0.83
SCHEMBL9248005 0.80 DNM1 (0.33) DNM1TSHRSMN1; SMN2OPRM1ALDH1A1
SCHEMBL9248004 0.80 DNM1 (0.33) DNM1TSHRSMN1; SMN2OPRM1ALDH1A1
SCHEMBL1410188 0.77 TSHR (0.50) DNM1TSHRSMN1; SMN2OPRM1ALDH1A1
SCHEMBL28153757 0.77 DNM1 (0.35) DNM1TSHRSMN1; SMN2OPRM1ALDH1A1
SCHEMBL24914687 0.77 DNM1 (0.35) DNM1TSHRSMN1; SMN2OPRM1ALDH1A1
SCHEMBL18629455 0.77 DNM1 (0.35) DNM1TSHRSMN1; SMN2OPRM1ALDH1A1
SCHEMBL1285427 0.77 TSHR (0.36) DNM1TSHRSMN1; SMN2OPRM1ALDH1A1
SCHEMBL3185161 0.76 DNM1 (0.47) DNM1TSHRSMN1; SMN2OPRM1ALDH1A1
SCHEMBL22345156 0.76 DNM1 (0.47) DNM1TSHRSMN1; SMN2OPRM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10202322-B2 Resorcinol derivatives SUTTER BAY HOSPITALS (US) 2019-02-12 US claimed
US-20180170846-A1 RESORCINOL DERIVATIVES SUTTER WEST BAY HOSPITALS 2018-06-21 US claimed
US-20130209483-A1 CANNABIDINOID DERIVATIVES SUTTER WEST BAY HOSPITALS (US) 2013-08-15 US claimed
EP-0004172-B1 BENZOCYCLOHEPTAPYRANS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM ELI LILLY AND COMPANY (US) 1982-04-07 EP claimed
US-10202322-B2 Resorcinol derivatives SUTTER BAY HOSPITALS (US) 2019-02-12 US disclosed
US-20180170846-A1 RESORCINOL DERIVATIVES SUTTER WEST BAY HOSPITALS 2018-06-21 US disclosed
US-9809521-B2 Cannabidinoid derivatives SUTTER WEST BAY HOSPITALS (US) 2017-11-07 US disclosed
US-20160376211-A1 CANNABIDINOID DERIVATIVES SUTTER WEST BAY HOSPITALS 2016-12-29 US disclosed
CN-103804687-B Phenyl polysiloxane and preparation method thereof for high-power LED encapsulation YANTAI DEBANG ADVANCED SILICON MATERIALS CO.,LTD. (CN) 2016-05-11 CN disclosed
US-9254272-B2 Resorcinol derivatives SUTTER WEST BAY HOSPITALS (US) 2016-02-09 US disclosed
US-9072917-B2 Linear alkyl esters and their use in cosmetic and/or pharmaceutical compositions COGNIS IP MANAGEMENT GMBH (DE) 2015-07-07 US disclosed
US-8642798-B2 Silacycle compounds and methods of use thereof THE TRUSTEE OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2014-02-04 US disclosed
EP-0004172-A1 Benzocycloheptapyrans, their preparation and pharmaceutical formulations containing them ELI LILLY AND COMPANY (US) 1979-09-19 EP disclosed
EP-0003883-A1 Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals ELI LILLY AND COMPANY (US) 1979-09-05 EP disclosed
US-4152450-A 9-Amino-dibenzopyrans ELI LILLY AND COMPANY (US) 1979-05-01 US disclosed
US-4152451-A HYPOTENSIVE AGENTS ELI LILLY AND COMPANY (US) 1979-05-01 US disclosed
US-4148809-A Process for preparing dl-cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones ELI LILLY AND COMPANY (US) 1979-04-10 US disclosed
US-4140701-A 2,6-Methano-2H-1-benzoxocins ELI LILLY AND COMPANY (US) 1979-02-20 US disclosed
US-4131614-A Process for preparing cis-hexahydrodibenzopyranones ELI LILLY AND COMPANY (US) 1978-12-26 US disclosed
US-4102902-A Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor ELI LILLY AND COMPANY (US) 1978-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10202322-B2 Resorcinol derivatives CNR1, CNR2, RCOR1 DNM1 2342/4885TSHR 3290/4885SMN1; SMN2 4124/4885
US-20130209483-A1 CANNABIDINOID DERIVATIVES CNR2, CNR1, GPR18 DNM1 1228/4885TSHR 4095/4885SMN1; SMN2 1784/4885
US-20160376211-A1 CANNABIDINOID DERIVATIVES CNR2, CNR1, GPR18 DNM1 1228/4885TSHR 4095/4885SMN1; SMN2 1784/4885
US-20180170846-A1 RESORCINOL DERIVATIVES CNR1, CNR2, RCOR1 DNM1 2342/4885TSHR 3290/4885SMN1; SMN2 4124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.