SCHEMBL10037527

SCHEMBL10037527

CC(NCCN)NC(=O)C(C)N1C(=O)C=CC1=O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CPB2 Q96IY4 2/20 0.34
▸ POLB P06746 1/20 0.33
▸ SLC1A2 P43004 2/20 0.31
▸ TERT O14746 2/20 0.31
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30269173 0.81 TERT (0.40) SLC1A2TERT
SCHEMBL17841877 0.81 TERT (0.40) SLC1A2TERT
SCHEMBL10037571 0.78 POLB (0.37) POLBSLC1A2MAPT
SCHEMBL13185397 0.78 POLB (0.37) POLBSLC1A2MAPT
SCHEMBL13448309 0.77 POLB (0.35) POLBSLC1A2
SCHEMBL2610530 0.76 POLB (0.36) POLBSLC1A2MAPT
SCHEMBL10037953 0.76 SLC1A2 (0.30) SLC1A2
SCHEMBL10037551 0.76 POLB (0.38) POLBSLC1A2MAPT
SCHEMBL12107536 0.76 CYP1A2 (0.43) POLBSLC1A2MAPT
SCHEMBL12421897 0.74 POLB (0.32) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124791-B2 Active energy ray curable liquid composition and liquid cartridge CANON KABUSHIKI KAISHA (JP) 2012-02-28 — — US disclosed
US-20100094024-A1 ACTIVE ENERGY RAY CURABLE LIQUID COMPOSITION AND LIQUID CARTRIDGE CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100094024-A1 ACTIVE ENERGY RAY CURABLE LIQUID COMPOSITION AND LIQUID CARTRIDGE C9, MLX, CHRM1 CPB2 1430/4885POLB 207/4885SLC1A2 933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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