Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 10/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131502 | 1.00 | MAPT (0.56) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL1131506 | 1.00 | MAPT (0.56) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| Sulfuric Acid Dimethyl Ester SCHEMBL27752564 | 0.87 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8494526 | 0.87 | MAPT (0.57) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8494529 | 0.87 | MAPT (0.57) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL5681841 | 0.86 | MAPT (0.48) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL5681840 | 0.86 | MAPT (0.48) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL13909197 | 0.83 | MAPT (0.47) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL3936770 | 0.81 | MAPT (0.61) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL3936772 | 0.81 | MAPT (0.61) | MAPTSMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235115-B1 | POLYMERIC HAIR DYES | BASF SE (DE) | 2013-10-16 | — | — | EP | disclosed |
| US-8097045-B2 | Polymeric hair dyes | BASF SE (DE) | 2012-01-17 | — | — | US | disclosed |
| US-8097045-B2 | Polymeric hair dyes | BASF SE (DE) | 2012-01-17 | — | — | US | disclosed |
| US-20110107525-A1 | POLYMERIC HAIR DYES | BASF SE (US) | 2011-05-12 | — | — | US | disclosed |
| US-20110107525-A1 | POLYMERIC HAIR DYES | BASF SE (US) | 2011-05-12 | — | — | US | disclosed |
| WO-2009090125-A1 | POLYMERIC HAIR DYES | BASF SE (DE) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110107525-A1 | POLYMERIC HAIR DYES | CYB5R3, CYC1, CBR1 | MAPT 3936/4885SMN1; SMN2 3347/4885NPC1 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.