Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936772 | 1.00 | MAPT (0.61) | MAPTPOLBMAPK1NPC1RAB9A | |
| SCHEMBL11288439 | 0.83 | MAPT (0.64) | MAPTPOLBMAPK1NPC1RAB9A | |
| SCHEMBL8494526 | 0.82 | MAPT (0.57) | MAPTPOLBMAPK1NPC1RAB9A | |
| SCHEMBL8494529 | 0.82 | MAPT (0.57) | MAPTPOLBMAPK1NPC1RAB9A | |
| SCHEMBL10037535 | 0.81 | MAPT (0.56) | MAPTPOLBMAPK1NPC1RAB9A | |
| SCHEMBL1131502 | 0.81 | MAPT (0.56) | MAPTPOLBMAPK1NPC1RAB9A | |
| SCHEMBL1131506 | 0.81 | MAPT (0.56) | MAPTPOLBMAPK1NPC1RAB9A | |
| SCHEMBL7662092 | 0.81 | ALDH1A1 (0.62) | MAPTPOLBMAPK1NPC1RAB9A | |
| SCHEMBL7662089 | 0.81 | ALDH1A1 (0.62) | MAPTPOLBMAPK1NPC1RAB9A | |
| SCHEMBL11494517 | 0.78 | MAPT (0.58) | MAPTPOLBMAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847250-B1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | PROCTER & GAMBLE (US) | 2009-12-23 | — | — | EP | disclosed |
| US-7513918-B2 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | THE PROCTER & GAMBLE COMPANY (US) | 2009-04-07 | — | — | US | disclosed |
| EP-1852104-A1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | Wella Aktiengesellschaft (DE) | 2007-11-07 | — | — | EP | disclosed |
| WO-2007119228-A2 | AGENTS FOR COLOURING KERATIN FIBRES COMPRISING ZWITTERIONIC AZOMETHINE DYES | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |
| US-20070245501-A1 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | WELLA OPERATIONS US, LLC | 2007-10-25 | — | — | US | disclosed |
| EP-1847250-A1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070245501-A1 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | KRT18, IK, RARG | MAPT 3818/4885POLB 3692/4885MAPK1 1150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.