Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.39 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | TAS2R8 | Q9NYW2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602 | 0.93 | ABCC3 (0.44) | HDAC1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL14779474 | 0.93 | ABCC3 (0.44) | HDAC1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL10038 | 0.92 | HDAC1 (0.40) | HDAC1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL10037 | 0.92 | HDAC1 (0.40) | HDAC1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL9917 | 0.87 | SCD5 (0.43) | HDAC1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL14778057 | 0.86 | HDAC1 (0.40) | HDAC1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL4476 | 0.86 | HDAC1 (0.40) | HDAC1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL16417063 | 0.83 | HDAC1 (0.41) | HDAC1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL16417065 | 0.83 | HDAC1 (0.41) | HDAC1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL3309 | 0.79 | SCD5 (0.45) | HDAC1ABCC3ABCC4ABCB11CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483251-A2 | POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041462-A2 | POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |