Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19476075 | 0.91 | MEN1 (0.64) | EGFRPIK3CADRD2TAS1R3TAS1R1 | |
| SCHEMBL6883379 | 0.91 | MEN1 (0.64) | EGFRPIK3CADRD2TAS1R3TAS1R1 | |
| SCHEMBL17149629 | 0.91 | MEN1 (0.64) | EGFRPIK3CADRD2TAS1R3TAS1R1 | |
| SCHEMBL17149616 | 0.88 | ALOX15 (0.59) | EGFRPIK3CADRD2TAS1R3TAS1R1 | |
| SCHEMBL10039654 | 0.88 | EGFR (0.57) | EGFRPIK3CADRD2TAS1R3TAS1R1 | |
| SCHEMBL10039688 | 0.88 | EGFR (0.57) | EGFRPIK3CADRD2TAS1R3TAS1R1 | |
| SCHEMBL10039793 | 0.88 | EGFR (0.57) | EGFRPIK3CADRD2TAS1R3TAS1R1 | |
| SCHEMBL6918437 | 0.86 | EGFR (0.58) | EGFRPIK3CADRD2TAS1R3TAS1R1 | |
| SCHEMBL17149618 | 0.86 | MEN1 (0.56) | EGFRPIK3CADRD2TAS1R3TAS1R1 | |
| SCHEMBL17149620 | 0.86 | TP53 (0.64) | DRD2MEN1KMT2ARCE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084971-A1 | INDOLE DERIVATIVES AS AGENTS AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE BACTERIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-06-28 | — | — | WO | disclosed |