Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 4/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CCKAR | P32238 | 1/20 | 0.57 |
| ▸ | PYGL | P06737 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19476075 | 1.00 | MEN1 (0.64) | MEN1KMT2ARCE1DRD2EGFR | |
| SCHEMBL17149629 | 1.00 | MEN1 (0.64) | MEN1KMT2ARCE1DRD2EGFR | |
| SCHEMBL10039654 | 0.92 | EGFR (0.57) | MEN1KMT2ARCE1DRD2EGFR | |
| SCHEMBL10039656 | 0.91 | EGFR (0.58) | MEN1KMT2ARCE1DRD2EGFR | |
| SCHEMBL17149616 | 0.89 | ALOX15 (0.59) | MEN1KMT2ARCE1DRD2EGFR | |
| SCHEMBL10039793 | 0.89 | EGFR (0.57) | MEN1KMT2ARCE1DRD2EGFR | |
| SCHEMBL10039688 | 0.89 | EGFR (0.57) | MEN1KMT2ARCE1DRD2EGFR | |
| SCHEMBL6918437 | 0.87 | EGFR (0.58) | MEN1KMT2ARCE1DRD2EGFR | |
| SCHEMBL17149787 | 0.87 | ALOX15 (0.56) | MEN1KMT2ARCE1DRD2EGFR | |
| SCHEMBL10039600 | 0.87 | EGFR (0.56) | MEN1KMT2ARCE1DRD2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1460064-A1 | Indole-2-carboxamide derivatives useful as beta-2 agonists | Pfizer Limited (GB) | 2004-09-22 | — | — | EP | disclosed |