Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222574 | 0.87 | MAPT (0.48) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL18537916 | 0.81 | MAPT (0.43) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL18537922 | 0.81 | MAPT (0.43) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL24359638 | 0.81 | MAPT (0.43) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL11432487 | 0.80 | MAPT (1.00) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL11135951 | 0.80 | MAPT (0.73) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL10039985 | 0.80 | MAPT (0.73) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL18537937 | 0.78 | MAPT (0.42) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL23822802 | 0.77 | KDM4E (0.44) | MAPTGAAMEN1KMT2AHTT | |
| SCHEMBL23822801 | 0.77 | KDM4E (0.44) | MAPTGAAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198923-B2 | Phosphate management with small molecules | Opko Ireland Global Holdings, Ltd. (KY) | 2015-12-01 | — | — | US | disclosed |
| US-20120028926-A1 | Phosphate Management with Small Molecules | CYTOCHROMA INC. (CA) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028926-A1 | Phosphate Management with Small Molecules | SLC34A2, PHPT1, SLC34A3 | MAPT 1907/4885GAA 306/4885MEN1 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.