Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23822801 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1POLBMAPTANPEP | |
| SCHEMBL31222574 | 0.89 | MAPT (0.48) | KDM4EALDH1A1POLBMAPTANPEP | |
| SCHEMBL18537916 | 0.82 | MAPT (0.43) | KDM4EALDH1A1POLBMAPTANPEP | |
| SCHEMBL24359638 | 0.82 | MAPT (0.43) | KDM4EALDH1A1POLBMAPTGABBR2 | |
| SCHEMBL18537922 | 0.82 | MAPT (0.43) | KDM4EALDH1A1POLBMAPTANPEP | |
| SCHEMBL27329595 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1POLBMAPTCYP1A2 | |
| SCHEMBL10040033 | 0.77 | MAPT (0.67) | KDM4EALDH1A1POLBMAPTANPEP | |
| SCHEMBL13992938 | 0.75 | HSD17B10 (0.44) | KDM4EALDH1A1POLBMAPTTSHR | |
| SCHEMBL16645399 | 0.75 | HSD17B10 (0.44) | KDM4EALDH1A1POLBMAPTTSHR | |
| SCHEMBL18537937 | 0.71 | MAPT (0.42) | KDM4EALDH1A1POLBMAPTANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021180969-A1 | CYCLIC PEPTIDES AND THEIR CONJUGATES FOR ADDRESSING ALPHA-V-BETA-6 INTEGRIN IN VIVO | Technische Universität München (DE) | 2021-09-16 | — | — | WO | disclosed |