Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.42 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10040283 | 0.96 | RECQL (0.49) | RECQLRAB9AESR1ESR2MAPK1 | |
| SCHEMBL10040280 | 0.94 | PTGER4 (0.48) | RECQLRAB9AESR1ESR2MAPK1 | |
| SCHEMBL15783226 | 0.93 | PTGER4 (0.48) | RECQLRAB9AESR1ESR2MAPK1 | |
| SCHEMBL10040279 | 0.92 | ESR1 (0.54) | RAB9AESR1ESR2MAPK1HTT | |
| SCHEMBL10040269 | 0.91 | ESR1 (0.56) | RAB9AESR1ESR2MAPK1HTT | |
| SCHEMBL15771378 | 0.90 | PTGER4 (0.48) | RECQLRAB9AESR1ESR2MAPK1 | |
| SCHEMBL10040270 | 0.88 | ESR1 (0.51) | RAB9AESR1ESR2MAPK1HTT | |
| SCHEMBL15771172 | 0.87 | PTGER4 (0.49) | RECQLRAB9AESR1ESR2MAPK1 | |
| SCHEMBL10040278 | 0.87 | ESR1 (0.52) | RAB9AESR1ESR2MAPK1HTT | |
| SCHEMBL19954857 | 0.85 | ESR1 (0.51) | RAB9AESR1ESR2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016449-A1 | PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20120016449-A1 | PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016449-A1 | PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS | TYR, PPOX, CRY1 | RECQL 683/4885RAB9A 4204/4885ESR1 1396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.