SCHEMBL10041207

SCHEMBL10041207

Bc1ccc(Cl)c(Cc2ccc(OCC)c(F)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 12/20 0.50
SLC5A1 P13866 5/20 0.50
KDM1A O60341 2/20 0.37
FFAR1 O14842 1/20 0.36
KCNQ3 O43525 1/20 0.35
KCNQ2 O43526 1/20 0.35
ADRA2A P08913 1/20 0.34
SLC5A11 Q8WWX8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1539332 0.84 SLC5A2 (0.50) SLC5A2SLC5A1KDM1A
SCHEMBL28680327 0.84 SLC5A2 (0.50) SLC5A2SLC5A1KDM1AFFAR1KCNQ3
SCHEMBL14608649 0.79 SLC5A2 (0.53) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL16601002 0.78 SLC5A2 (0.45) SLC5A2SLC5A1KDM1AFFAR1KCNQ3
SCHEMBL12801465 0.78 KDM1A (0.50) KDM1AKCNQ3KCNQ2
SCHEMBL10041206 0.76 CYP3A4 (0.44)
SCHEMBL13979827 0.74 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL16600928 0.73 SLC5A2 (0.41) SLC5A2SLC5A1KDM1AKCNQ3KCNQ2
SCHEMBL12257514 0.73 SLC5A2 (0.73) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL14954899 0.72 SLC5A2 (0.40) SLC5A2SLC5A1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012019496-A1 C-ARYL GLUCOSIDE DERIVATIVES, PREPARATION RPOCESS AND PHARMACEUTICAL USE THEREOF 上海恒瑞医药有限公司 (CN) 2012-02-16 WO disclosed