Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13513329 | 0.84 | HTT (0.49) | KDM1AL3MBTL1HTTKDM4EMAPT | |
| SCHEMBL12269151 | 0.83 | THRA (0.44) | KDM1AL3MBTL1CYP1A2CYP2C19TDP1 | |
| SCHEMBL10187103 | 0.81 | KDM4E (0.46) | L3MBTL1PDE4AKDM4EMAPTGAA | |
| SCHEMBL13088885 | 0.81 | KDM1A (0.34) | KDM1AL3MBTL1TUBB1HTTALDH1A1 | |
| SCHEMBL1547577 | 0.79 | L3MBTL1 (0.53) | KDM1AL3MBTL1TUBB1KCNQ3KCNQ2 | |
| SCHEMBL9484876 | 0.79 | L3MBTL1 (0.53) | KDM1AL3MBTL1TUBB1HTTKDM4E | |
| SCHEMBL13761018 | 0.79 | ESR1 (0.47) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| Water SCHEMBL27753859 | 0.78 | S1PR4 (0.38) | L3MBTL1HTTKDM4EMAPTALDH1A1 | |
| SCHEMBL10041207 | 0.78 | SLC5A2 (0.50) | KDM1AKCNQ3KCNQ2 | |
| SCHEMBL2053269 | 0.78 | NQO1 (0.52) | KDM1AL3MBTL1TUBB1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011040373-A1 | LIQUID CRYSTALLINE COMPOUND WITH NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION USING SAME, AND LIQUID CRYSTAL DISPLAY ELEMENT | チッソ株式会社 (JP) | 2011-04-07 | — | — | WO | disclosed |