SCHEMBL16601002

SCHEMBL16601002

CCOc1ccc(Cc2c[c]ccc2Cl)cc1F

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 5/20 0.45
SLC5A1 P13866 1/20 0.45
KDM1A O60341 2/20 0.36
KCNQ3 O43525 1/20 0.34
KCNQ2 O43526 1/20 0.34
FFAR1 O14842 1/20 0.34
P2RX3 P56373 1/20 0.34
GPR52 Q9Y2T5 1/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
LTA4H P09960 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MITF O75030 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16600692 0.78 SLC5A2 (0.47) SLC5A2SLC5A1KDM4ELMNASMN1; SMN2
SCHEMBL28680327 0.78 SLC5A2 (0.50) SLC5A2SLC5A1KDM1AKCNQ3KCNQ2
SCHEMBL1539332 0.78 SLC5A2 (0.50) SLC5A2SLC5A1KDM1AALDH1A1LMNA
SCHEMBL10041207 0.78 SLC5A2 (0.50) SLC5A2SLC5A1KDM1AKCNQ3KCNQ2
SCHEMBL16600928 0.77 SLC5A2 (0.41) SLC5A2SLC5A1KDM1AKCNQ3KCNQ2
SCHEMBL27788342 0.77 SLC5A2 (0.46) SLC5A2SLC5A1KDM4ELMNASMN1; SMN2
Magnesium Chloride Anhydrous SCHEMBL29084875 0.74 SLC5A2 (0.44) SLC5A2SLC5A1KDM4ESMN1; SMN2
SCHEMBL27788263 0.74 SLC5A2 (0.44) SLC5A2SLC5A1KDM4ESMN1; SMN2
Chlorolithium SCHEMBL29084912 0.72 SLC5A2 (0.42) SLC5A2SLC5A1KDM4ESMN1; SMN2
Chlorolithium SCHEMBL29084967 0.72 SLC5A2 (0.42) SLC5A2SLC5A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015043473-A1 GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE SUNSHINE LAKE PHARMA CO., LTD. (CN) 2015-04-02 WO disclosed