SCHEMBL10041296

SCHEMBL10041296

COc1cc(CCN)cc(O)c1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.70
TAAR1 Q96RJ0 2/20 0.70
MAPK1 P28482 1/20 0.70
LMNA P02545 2/20 0.68
CYP1A2 P05177 1/20 0.68
CYP3A4 P08684 1/20 0.68
NFKB1 P19838 1/20 0.68
GLA P06280 1/20 0.68
MEN1 O00255 1/20 0.66
APEX1 P27695 1/20 0.66
KMT2A Q03164 1/20 0.66
HTR2A P28223 4/20 0.66
HTR2C P28335 2/20 0.66
HTR2B P41595 2/20 0.66
AKR1B1 P15121 1/20 0.61
KDM4E B2RXH2 1/20 0.58
ATM Q13315 1/20 0.58
ADRB2 P07550 1/20 0.56
TNKS2 Q9H2K2 2/20 0.53
PTPN1 P18031 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1467120 0.94 HTR2A (0.68) TSHRTAAR1MAPK1LMNACYP1A2
Hydrochloric Acid SCHEMBL7370392 0.92 TAAR1 (0.68) TSHRTAAR1MAPK1LMNACYP1A2
SCHEMBL17263518 0.88 AKR1B1 (0.76) TSHRTAAR1MAPK1LMNACYP1A2
SCHEMBL25374970 0.87 HTR2A (0.76) TSHRTAAR1MAPK1LMNACYP1A2
SCHEMBL30101541 0.87 HTR2A (0.76) TSHRTAAR1MAPK1LMNACYP1A2
SCHEMBL7045244 0.86 TSHR (0.56) TSHRTAAR1MAPK1LMNACYP1A2
SCHEMBL3041350 0.84 AKR1B1 (0.61) TSHRTAAR1MAPK1LMNACYP1A2
Hydrochloric Acid SCHEMBL30771790 0.84 LMNA (0.58) TSHRTAAR1MAPK1LMNACYP1A2
SCHEMBL29286368 0.83 AKR1B1 (0.81) TSHRTAAR1MAPK1LMNACYP1A2
Phenol SCHEMBL28390260 0.83 TAAR1 (0.58) TSHRTAAR1MAPK1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3930862-A DYE DEVELOPER TRANSFER PHOTOSENSITIVE MATERIAL WITH SUBSTITUTED CATECHOL AUXILIARY DEVELOPER FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed
EP-4500274-B1 IRREVERSIBLE ORGANIC ELECTROCHROMIC MATERIALS UNIV WIEN (AT) 2026-01-14 EP disclosed
US-20250189855-A1 IRREVERSIBLE ORGANIC ELECTROCHROMIC MATERIALS UNIVERSITAET WIEN (AT) 2025-06-12 US disclosed
EP-4500274-A1 IRREVERSIBLE ORGANIC ELECTROCHROMIC MATERIALS Universität Wien (AT) 2025-02-05 EP disclosed
WO-2024246905-A1 ENZYMES, POLYNUCLEOTIDES ENCODING SAME, AND METHODS OF USING SAME FOR PRODUCING MESCALINE YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2024-12-05 WO disclosed
WO-2023180536-A1 IRREVERSIBLE ORGANIC ELECTROCHROMIC MATERIALS UNIVERSITAET WIEN (AT) 2023-09-28 WO disclosed
EP-2407167-A2 Therapeutic agent for neurodegenerative disease National University Corporation Hokkaido University (JP) 2012-01-18 EP disclosed
EP-1974732-A1 THERAPEUTIC AGENT FOR NEURODEGENERATIVE DISEASE National University Corporation Hokkaido University (JP) 2008-10-01 EP disclosed
US-3930862-A DYE DEVELOPER TRANSFER PHOTOSENSITIVE MATERIAL WITH SUBSTITUTED CATECHOL AUXILIARY DEVELOPER FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed