Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30771790 | 0.98 | LMNA (0.58) | TSHRTAAR1MAPK1LMNACYP1A2 | |
| SCHEMBL1999631 | 0.91 | AKR1B1 (0.52) | TSHRTAAR1MAPK1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL28020800 | 0.89 | LMNA (0.52) | TSHRTAAR1MAPK1LMNACYP1A2 | |
| Iodide SCHEMBL27584793 | 0.89 | AKR1B1 (0.50) | TSHRTAAR1MAPK1LMNACYP1A2 | |
| SCHEMBL10041296 | 0.86 | TSHR (0.70) | TSHRTAAR1MAPK1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL30771793 | 0.85 | TAAR1 (0.49) | TSHRTAAR1MAPK1LMNACYP1A2 | |
| SCHEMBL3566176 | 0.84 | HTR2A (0.53) | TSHRTAAR1MAPK1LMNACYP1A2 | |
| SCHEMBL27873502 | 0.84 | TAAR1 (0.44) | TSHRTAAR1MAPK1LMNACYP1A2 | |
| SCHEMBL27873506 | 0.81 | TRPV1 (0.51) | TSHRTAAR1MAPK1LMNANFKB1 | |
| SCHEMBL17263518 | 0.81 | AKR1B1 (0.76) | TSHRTAAR1MAPK1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1437580-A | 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants | HAARMANN & REIMER GMBH (DE) | 2003-08-20 | — | — | CN | claimed |
| US-20030139470-A1 | 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants | HAARMANN & REIMER GMBH (DE) | 2003-07-24 | — | — | US | claimed |
| EP-1296941-A2 | 3,4-DIHYDROXYBENZYL-SUBSTITUTED CARBONIC ACID DERIVATIVES AND THE USE THEREOF AS ANTIOXIDANTS | HAARMANN & REIMER GMBH (DE) | 2003-04-02 | — | — | EP | claimed |
| WO-2001098235-A2 | 3,4-DIHYDROXYBENZYL-SUBSTITUTED CARBONIC ACID DERIVATIVES AND THE USE THEREOF AS ANTIOXIDANTS | HAARMANN & REIMER GMBH (DE) | 2001-12-27 | — | — | WO | claimed |
| CN-1437580-A | 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants | HAARMANN & REIMER GMBH (DE) | 2003-08-20 | — | — | CN | disclosed |
| US-20030139470-A1 | 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants | HAARMANN & REIMER GMBH (DE) | 2003-07-24 | — | — | US | disclosed |
| EP-1296941-A2 | 3,4-DIHYDROXYBENZYL-SUBSTITUTED CARBONIC ACID DERIVATIVES AND THE USE THEREOF AS ANTIOXIDANTS | HAARMANN & REIMER GMBH (DE) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001098235-A2 | 3,4-DIHYDROXYBENZYL-SUBSTITUTED CARBONIC ACID DERIVATIVES AND THE USE THEREOF AS ANTIOXIDANTS | HAARMANN & REIMER GMBH (DE) | 2001-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139470-A1 | 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants | TYR, HAAO, TH | TSHR 4451/4885TAAR1 1025/4885MAPK1 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.