SCHEMBL10041508

SCHEMBL10041508

CC1(C)c2ccccc2-c2ccc(Nc3ccc(-c4ccc(Nc5ccc6c(c5)C(C)(C)c5ccccc5-6)cc4)cc3)cc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 13/20 0.50
APP P05067 1/20 0.37
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 1/20 0.35
AR P10275 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 2/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
ALOX12 P18054 1/20 0.34
PTGS1 P23219 1/20 0.34
SLC6A2 P23975 1/20 0.34
MAPK1 P28482 1/20 0.34
PTGS2 P35354 1/20 0.34
HTR2B P41595 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HPGD P15428 2/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737911 1.00 PDK2 (0.50) PDK2APPALDH1A1MEN1AR
SCHEMBL15146297 0.97 PDK2 (0.55) PDK2APPALDH1A1MEN1AR
SCHEMBL20174027 0.97 PDK2 (0.51) PDK2APPALDH1A1MEN1AR
SCHEMBL30935420 0.97 PDK2 (0.51) PDK2APPALDH1A1MEN1AR
SCHEMBL9916947 0.97 PDK2 (0.51) PDK2APPALDH1A1MEN1AR
SCHEMBL13367405 0.97 PDK2 (0.48) PDK2APP
SCHEMBL169589 0.97 PDK2 (0.51) PDK2APPALDH1A1MEN1AR
SCHEMBL29365024 0.97 PDK2 (0.51) PDK2APPALDH1A1MEN1AR
SCHEMBL16366420 0.94 PDK2 (0.49) PDK2APP
SCHEMBL15892494 0.94 PDK2 (0.46) PDK2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11196009-B2 Fluorene derivative, organic light emitting device using same, and manufacturing method therefor LG CHEM, LTD. 2021-12-07 US disclosed
EP-3366673-B1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEMICAL LTD (KR) 2021-09-29 EP disclosed
EP-3495344-B1 FLUORENE DERIVATIVE, ORGANIC LIGHT EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR LG CHEMICAL LTD (KR) 2021-09-29 EP disclosed
EP-2603541-B1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2021-04-21 EP disclosed
EP-2603540-B1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2021-04-21 EP disclosed
US-10954218-B2 Carbazole derivative and organic light emitting device using same LG CHEM, LTD. 2021-03-23 US disclosed
US-20190214568-A1 Fluorene Derivative, Organic Light Emitting Device Using Same, And Manufacturing Method Therefor LG CHEM, LTD. (KR) 2019-07-11 US disclosed
EP-3495344-A2 FLUORENE DERIVATIVE, ORGANIC LIGHT EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR LG Chem, Ltd. (KR) 2019-06-12 EP disclosed
US-20180354933-A1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2018-12-13 US disclosed
US-9755165-B2 Silsesquioxane compound, organic light emitting element, display apparatus, image information processing apparatus, and image forming apparatus CANON KABUSHIKI KAISHA (JP) 2017-09-05 US disclosed
US-9102797-B2 Polymers with carbazole structural units MERCK PATENT GMBH (DE) 2015-08-11 US disclosed
US-8969512-B2 Polymers having carbazole structural units MERCK PATENT GMBH (DE) 2015-03-03 US disclosed
US-8969512-B2 Polymers having carbazole structural units MERCK PATENT GMBH (DE) 2015-03-03 US disclosed
WO-2014163028-A1 SILSESQUIOXANE COMPOUND, ORGANIC LIGHT EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION PROCESSING APPARATUS, AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-10-09 WO disclosed
US-20130150527-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS SAMSUNG DISPLAY CO., LTD. (KR) 2013-06-13 US disclosed
US-20130150527-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS SAMSUNG DISPLAY CO., LTD. (KR) 2013-06-13 US disclosed
US-20130137818-A1 POLYMERS HAVING CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2013-05-30 US disclosed
US-20130137818-A1 POLYMERS HAVING CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2013-05-30 US disclosed
WO-2012019724-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2012-02-16 WO disclosed
WO-2012019725-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2012-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11196009-B2 Fluorene derivative, organic light emitting device using same, and manufacturing method therefor NOTUM, FTO, FARSB PDK2 3117/4885APP 1385/4885ALDH1A1 219/4885
US-20180354933-A1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING SAME CYP3A4, CYP2C19, CYP2C9 PDK2 1509/4885APP 3401/4885ALDH1A1 278/4885
US-20190214568-A1 Fluorene Derivative, Organic Light Emitting Device Using Same, And Manufacturing Method Therefor NOTUM, FTO, FARSB PDK2 3117/4885APP 1385/4885ALDH1A1 219/4885
US-10954218-B2 Carbazole derivative and organic light emitting device using same CYP3A4, CYP2C19, CYP2C9 PDK2 1509/4885APP 3401/4885ALDH1A1 278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.