⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878259 | 0.78 | — | — | |
| SCHEMBL25949593 | 0.76 | — | — | |
| SCHEMBL24672977 | 0.72 | ANPEP (0.31) | — | |
| SCHEMBL14175036 | 0.72 | — | — | |
| SCHEMBL4471926 | 0.72 | — | — | |
| SCHEMBL19456013 | 0.70 | — | — | |
| SCHEMBL24477200 | 0.70 | — | — | |
| SCHEMBL24648750 | 0.70 | — | — | |
| SCHEMBL9887404 | 0.70 | — | — | |
| SCHEMBL11310286 | 0.70 | DDAH1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288548-B2 | Oxazolo[5-4-b]pyridin-5-yl compounds | ELI LILLY AND COMPANY (US) | 2012-10-16 | — | — | US | disclosed |
| US-20120142724-A1 | OXAZOLO[5-4-b]PYRIDIN-5-YL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2012-06-07 | — | — | US | disclosed |