Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | F13A1 | P00488 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | THPO | P40225 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11309907 | 0.81 | CA12 (0.38) | SMN1; SMN2CASP2CA12F13A1CA2 | |
| SCHEMBL6220142 | 0.81 | CA12 (0.38) | SMN1; SMN2CASP2CA12F13A1CA2 | |
| SCHEMBL21799679 | 0.77 | DNM1 (0.35) | CASP2CA12F13A1CA2CYP1A2 | |
| SCHEMBL6891737 | 0.77 | CA12 (0.52) | SMN1; SMN2CASP2CA12F13A1CA2 | |
| SCHEMBL13978118 | 0.76 | PAOX (0.35) | DDAH1SLC6A4SMN1; SMN2CA12F13A1 | |
| SCHEMBL25003626 | 0.75 | CA12 (0.50) | SMN1; SMN2CASP2CA12F13A1CA2 | |
| SCHEMBL4539635 | 0.75 | DNM1 (0.39) | MEN1KMT2ATSHR | |
| SCHEMBL6217773 | 0.75 | CA12 (0.50) | SMN1; SMN2CASP2CA12F13A1CA2 | |
| SCHEMBL14163241 | 0.75 | OPRM1 (0.34) | SMN1; SMN2CASP2CA12F13A1CA2 | |
| SCHEMBL28100277 | 0.74 | CA12 (0.40) | SMN1; SMN2CASP2CA12F13A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267102-A | Bleomycin group antibiotics | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-05-12 | — | — | US | disclosed |
| US-RE30451-E | ANTITUMOR AGENTS | Zaidan Jojin Biseibutsu Kagaku Kenkyu Kai (JP) | 1980-12-16 | — | — | US | disclosed |