Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517580 | 0.98 | TSHR (0.46) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL10013491 | 0.96 | TSHR (0.44) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL10013495 | 0.93 | TSHR (0.46) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL10013496 | 0.92 | TSHR (0.41) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL12567322 | 0.90 | TSHR (0.40) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL13380262 | 0.82 | TSHR (0.40) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL15367919 | 0.79 | TSHR (0.50) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL6311761 | 0.77 | TSHR (0.48) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL12567323 | 0.77 | MAOA (0.32) | — | |
| SCHEMBL24357611 | 0.77 | MAPT (0.41) | TSHRPPARDMAPTHTTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029224-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES | BROMINE COMPOUNDS LTD. (IL) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029224-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES | PIK3CA, PIP5K1B, PIP5K1C | TSHR 640/4885PPARD 3354/4885TP53 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.