SCHEMBL517580

SCHEMBL517580

CCOP(=O)(Cc1c(Br)c(Br)c(Br)c(Br)c1Br)OCC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
PPARD Q03181 2/20 0.40
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.35
EGFR P00533 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10013491 0.98 TSHR (0.44) TSHRPPARDTP53TDP1MAPT
SCHEMBL10041879 0.98 TSHR (0.48) TSHRPPARDTP53TDP1MAPT
SCHEMBL10013495 0.96 TSHR (0.46) TSHRPPARDTP53TDP1MAPT
SCHEMBL12567322 0.92 TSHR (0.40) TSHRPPARDTP53TDP1MAPT
SCHEMBL10013496 0.90 TSHR (0.41) TSHRPPARDTP53TDP1MAPT
SCHEMBL13380262 0.80 TSHR (0.40) TSHRPPARDTP53TDP1MAPT
SCHEMBL12567323 0.80 MAOA (0.32)
SCHEMBL10013493 0.79 CYP3A4 (0.45) TSHR
SCHEMBL29087265 0.78 TSHR (0.58) TSHRPPARDTP53TDP1KMT2A
SCHEMBL15367919 0.77 TSHR (0.50) TSHRPPARDTP53TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120029224-A1 PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES BROMINE COMPOUNDS LTD. (IL) 2012-02-02 US claimed
WO-2010046899-A2 IMPROVED FLAME RETARDATION OF TEXTILES BY HALOGENATED ARYL PHOSPHONATES BROMINE COMPOUNDS LTD. (IL) 2010-04-29 WO claimed
WO-2010046898-A1 A PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES BROMINE COMPOUNDS LTD. (IL) 2010-04-29 WO claimed
CN-114574983-A Flame-retardant slurry and preparation method and application thereof 苏州世名科技股份有限公司 2022-06-03 CN disclosed
US-8405069-B2 Printable thin-film transistors with high dielectric constant gate insulators and methods for producing same GEORGIA TECH RESEARCH CORPORATION (US) 2013-03-26 US disclosed
US-8405069-B2 Printable thin-film transistors with high dielectric constant gate insulators and methods for producing same GEORGIA TECH RESEARCH CORPORATION (US) 2013-03-26 US disclosed
US-8405069-B2 Printable thin-film transistors with high dielectric constant gate insulators and methods for producing same GEORGIA TECH RESEARCH CORPORATION (US) 2013-03-26 US disclosed
US-20120029224-A1 PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES BROMINE COMPOUNDS LTD. (IL) 2012-02-02 US disclosed
US-20120029224-A1 PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES BROMINE COMPOUNDS LTD. (IL) 2012-02-02 US disclosed
US-20120029224-A1 PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES BROMINE COMPOUNDS LTD. (IL) 2012-02-02 US disclosed
US-7960456-B2 Halogenated phosphonates, processes for their preparation and their use as flame retardants BROMINE COMPOUNDS LTD. (IL) 2011-06-14 US disclosed
US-20100051917-A1 PRINTABLE THIN-FILM TRANSISTORS WITH HIGH DIELECTRIC CONSTANT GATE INSULATORS AND METHODS FOR PRODUCING SAME NATIONAL SCIENCE FOUNDATION 2010-03-04 US disclosed
US-20100051917-A1 PRINTABLE THIN-FILM TRANSISTORS WITH HIGH DIELECTRIC CONSTANT GATE INSULATORS AND METHODS FOR PRODUCING SAME NATIONAL SCIENCE FOUNDATION 2010-03-04 US disclosed
US-20100027192-A1 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION 2010-02-04 US disclosed
US-20100027192-A1 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION 2010-02-04 US disclosed
US-20100027192-A1 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION 2010-02-04 US disclosed
WO-2008060534-A1 PRINTABLE THIN-FILM TRANSISTORS WITH HIGH DIELECTRIC CONSTANT GATE INSULATORS AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION (US) 2008-05-22 WO disclosed
WO-2008060534-A1 PRINTABLE THIN-FILM TRANSISTORS WITH HIGH DIELECTRIC CONSTANT GATE INSULATORS AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION (US) 2008-05-22 WO disclosed
EP-1888311-A2 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION (US) 2008-02-20 EP disclosed
WO-2006124670-A2 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION (US) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100027192-A1 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME NCL, PNN, NCDN TSHR 1403/4885PPARD 4559/4885TP53 2461/4885
US-20120029224-A1 PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES PIK3CA, PIP5K1B, PIP5K1C TSHR 640/4885PPARD 3354/4885TP53 3006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.