Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 3/20 | 0.38 |
| ▸ | ATP4B | P51164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963126 | 1.00 | RAB9A (0.42) | RAB9ATLR8TLR7CYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3181001 | 0.98 | RAB9A (0.44) | RAB9ATLR8TLR7CYP2C9ALDH1A1 | |
| SCHEMBL3186943 | 0.89 | TLR8 (0.36) | RAB9ATLR8TLR7CYP2C9ALDH1A1 | |
| SCHEMBL27863553 | 0.87 | SMN1; SMN2 (0.43) | RAB9ATLR8TLR7CYP2C9ALDH1A1 | |
| SCHEMBL3177121 | 0.85 | DYRK1A (0.35) | RAB9ATLR8TLR7CYP2C9ALDH1A1 | |
| SCHEMBL11918960 | 0.84 | RAB9A (0.42) | RAB9ATLR8TLR7CYP2C9ALDH1A1 | |
| SCHEMBL9079044 | 0.82 | RAB9A (0.41) | RAB9ATLR8TLR7CYP2C9ALDH1A1 | |
| SCHEMBL17434630 | 0.82 | RAB9A (0.41) | RAB9ATLR8TLR7CYP2C9ALDH1A1 | |
| SCHEMBL29446629 | 0.82 | RAB9A (0.41) | RAB9ATLR8TLR7CYP2C9ALDH1A1 | |
| SCHEMBL29694096 | 0.82 | RAB9A (0.41) | RAB9ATLR8TLR7CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109354587-A | The preparation method and Pantoprazole Sodium of Pantoprazole Sodium | 成都天台山制药有限公司 | 2019-02-19 | — | — | CN | claimed |
| CN-104557692-B | A kind of preparation method of pantoprazole intermediate 2- chloromethyls -3,4- dimethoxy pyridine hydrochlorides | 寿光富康制药有限公司 | 2018-08-21 | — | — | CN | claimed |
| CN-108191745-A | The preparation method of 2- methylol -3,4- dimethoxy-pyridines | 滁州学院 | 2018-06-22 | — | — | CN | claimed |
| CN-107011252-B | The method for drawing azole intermediate and drug is prepared using the green technology for substituting the poisonous and harmful substances such as phosgene, thionyl chloride | 浙江工业大学 | 2018-06-08 | — | — | CN | claimed |
| CN-107011252-A | The method for drawing azole intermediate and medicine is prepared using the green technology for substituting the poisonous and harmful substances such as phosgene, thionyl chloride | 浙江工业大学 | 2017-08-04 | — | — | CN | claimed |
| CN-104557692-A | Preparation method of pantoprazole intermediate 2-chloromethyl-3,4-dimethoxy pyridine hydrochloride | Shouguang fukang pharmaceutical co ltd | 2015-04-29 | — | — | CN | claimed |
| CN-101875629-A | Industrial preparation method of pantoprazole intermediate pyridine hydrochloride | NANJING YUANHUA TECHNOLOGY CONSULTATION CO LTD | 2010-11-03 | — | — | CN | claimed |
| WO-2025085492-A1 | BORANE REDUCING REAGENTS | EXACT SCIENCES CORPORATION (US) | 2025-04-24 | — | — | WO | disclosed |
| CN-118324772-A | Synthesis method and intermediate of furan [3,2-b ] pyridine derivative | 北京颖诺凯胜科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115819403-A | Preparation method of pantoprazole sodium | 安徽普利药业有限公司 | 2023-03-21 | — | — | CN | disclosed |
| US-11241013-B2 | Benzimidazole compounds as agricultural chemicals | REDAG CROP PROT LTD (GB) | 2022-02-08 | — | — | US | disclosed |
| US-11224224-B2 | Thiobenzoimidazole as fungicides | REDAG CROP PROTECTION LTD. (GB) | 2022-01-18 | — | — | US | disclosed |
| US-20210204547-A1 | BENZIMIDAZOLE COMPOUNDS AS AGRICULTURAL CHEMICALS | REDAG CROP PROT LTD (GB) | 2021-07-08 | — | — | US | disclosed |
| US-4185103-A | ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-01-22 | — | — | US | disclosed |
| EP-0004793-A2 | 2-nitro aminopyrimidone derivatives, a process for their preparation and their use to prepare 2-aminopyrimidone derivatives which have histamine H2-antagonist activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-10-17 | — | — | EP | disclosed |
| US-4159329-A | BLOCKING AGENTS, ANTAGONISTS, ANTIHISTAMINES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-06-26 | — | — | US | disclosed |
| US-4156727-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-29 | — | — | US | disclosed |
| US-4154838-A | ANTIHISTAMINE | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-15 | — | — | US | disclosed |
| US-4154834-A | HETEROCYCLIC-(THIO)ALKYLAMINO SUBSTITUTED-4-PYRIMIDONE OR -THIONES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-15 | — | — | US | disclosed |
| US-4145546-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11224224-B2 | Thiobenzoimidazole as fungicides | CYP1B1, CYP51A1, CYP1A2 | RAB9A 3497/4885TLR8 4016/4885TLR7 3996/4885 |
| US-11241013-B2 | Benzimidazole compounds as agricultural chemicals | CYP3A4, CYP2C8, CYP2E1 | RAB9A 4057/4885TLR8 3942/4885TLR7 4779/4885 |
| US-20210204547-A1 | BENZIMIDAZOLE COMPOUNDS AS AGRICULTURAL CHEMICALS | CYP3A4, CYP2C8, CYP2E1 | RAB9A 4057/4885TLR8 3942/4885TLR7 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.