SCHEMBL29446629

SCHEMBL29446629

COc1ccnc(CCl)c1OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
ATP4A P20648 5/20 0.37
ATP4B P51164 5/20 0.37
CYP2C9 P11712 3/20 0.37
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
CYP3A4 P08684 4/20 0.36
LMNA P02545 3/20 0.36
PDE10A Q9Y233 3/20 0.36
CYP1A2 P05177 2/20 0.36
ALOX15 P16050 2/20 0.36
USP2 O75604 2/20 0.36
MAPK1 P28482 2/20 0.36
PDE3B Q13370 2/20 0.36
PDE3A Q14432 2/20 0.36
HIF1A Q16665 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2690888 1.00 RAB9A (0.41) RAB9ASMN1; SMN2ALDH1A1KDM4ETDP1
Hydrochloric Acid SCHEMBL1002426 0.98 RAB9A (0.43) RAB9ASMN1; SMN2ALDH1A1KDM4ETDP1
Hydrochloric Acid SCHEMBL28857260 0.98 RAB9A (0.43) RAB9ASMN1; SMN2ALDH1A1KDM4ETDP1
Hydrochloric Acid SCHEMBL29362717 0.98 RAB9A (0.43) RAB9ASMN1; SMN2ALDH1A1KDM4ETDP1
Hydrochloric Acid SCHEMBL28044243 0.90 RAB9A (0.39) RAB9ASMN1; SMN2ALDH1A1KDM4ETDP1
Hydrochloric Acid SCHEMBL3169911 0.88 RAB9A (0.37) RAB9ASMN1; SMN2ALDH1A1KDM4ETDP1
SCHEMBL1004190 0.82 RAB9A (0.42) RAB9ASMN1; SMN2ALDH1A1KDM4EATP4A
SCHEMBL30963126 0.82 RAB9A (0.42) RAB9ASMN1; SMN2ALDH1A1KDM4EATP4A
SCHEMBL11918960 0.82 RAB9A (0.42) RAB9ASMN1; SMN2ALDH1A1KDM4EATP4A
Hydrochloric Acid SCHEMBL3170719 0.82 RAB9A (0.33) RAB9ASMN1; SMN2ALDH1A1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4728019-A1 A MICROWAVE CARBONIZATION ASSEMBLY AND METHOD FOR EXTRACTING COMPONENTS FROM RUBBER Sable Rubber IP Pty Limited (AU) 2026-04-22 EP disclosed
EP-4695236-A1 SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2026-02-18 EP disclosed
WO-2024257019-A1 A MICROWAVE CARBONIZATION ASSEMBLY AND METHOD FOR EXTRACTING COMPONENTS FROM RUBBER Molectra Rubber IP Pty Ltd (AU) 2024-12-19 WO disclosed
CN-115867546-B Salt and crystalline forms of GLP-1R agonists and uses thereof 上海齐鲁锐格医药研发有限公司 2024-10-18 CN disclosed
WO-2024216094-A1 SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS, INC. (US) 2024-10-17 WO disclosed
CN-118324772-A Synthesis method and intermediate of furan [3,2-b ] pyridine derivative 北京颖诺凯胜科技有限公司 2024-07-12 CN disclosed
CN-117715906-A Glucagon-like peptide-1 receptor modulators and uses thereof 和博医药有限公司 2024-03-15 CN disclosed
CN-117043154-A GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof 卡莫特医疗有限公司 2023-11-10 CN disclosed
CN-116507326-A Compounds as GLP-1R agonists 拓臻制药公司 2023-07-28 CN disclosed
US-20230192708-A1 2,4,6,7-TETRAHYDRO-PYRAZOLO[4,3-D]PYRIMIDIN-5-ONE DERIVATIVES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS FOR TREATING VASCULITIS AND INFLAMMATORY DISEASES IDORSIA PHARMACEUTICALS LTD (CH) 2023-06-22 US disclosed
CN-113227068-B GLP-1R agonists and uses thereof 上海齐鲁锐格医药研发有限公司 2023-06-13 CN disclosed
CN-114213424-B Synthesis method of furan [3,2-b ] pyridine derivative 杭州高光制药有限公司 2023-05-26 CN disclosed
CN-115867546-A Salts and crystalline forms of GLP-1R agonists and uses thereof 上海齐鲁锐格医药研发有限公司 2023-03-28 CN disclosed
US-11608341-B2 Substituted tetrahydropyrazolo[3,4-d]pyrimidines and tetrahydropyrazolo[4,3-d]pyrimidines as C5A receptor modulators IDORSIA PHARMACEUTICALS LTD. (CH) 2023-03-21 US disclosed
CN-115697999-A Heterocyclic GLP-1 agonists 加舒布鲁姆生物公司 2023-02-03 CN disclosed
CN-114685514-A Novel amide pyrrole compound and application thereof in medicines 广东东阳光药业有限公司 2022-07-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192708-A1 2,4,6,7-TETRAHYDRO-PYRAZOLO[4,3-D]PYRIMIDIN-5-ONE DERIVATIVES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS FOR TREATING VASCULITIS AND INFLAMMATORY DISEASES C3AR1, C5AR1, C5AR2 RAB9A 1238/4885SMN1; SMN2 4595/4885ALDH1A1 2010/4885
US-11608341-B2 Substituted tetrahydropyrazolo[3,4-d]pyrimidines and tetrahydropyrazolo[4,3-d]pyrimidines as C5A receptor modulators C5AR1, C3AR1, C5AR2 RAB9A 1399/4885SMN1; SMN2 4565/4885ALDH1A1 3015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.