⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43270 | 0.71 | TSHR (0.39) | — | |
| SCHEMBL15746931 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL1325484 | 0.66 | — | — | |
| SCHEMBL10546696 | 0.65 | — | — | |
| SCHEMBL5720348 | 0.65 | — | — | |
| SCHEMBL4666457 | 0.64 | — | — | |
| SCHEMBL727529 | 0.64 | TSHR (0.31) | — | |
| SCHEMBL677442 | 0.64 | TSHR (0.35) | — | |
| SCHEMBL7781722 | 0.63 | — | — | |
| SCHEMBL17004061 | 0.62 | NAALAD2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8092821-B2 | Medical devices having polymeric regions with improved adhesion | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-7897171-B2 | Medical devices having improved mechanical performance | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897170-B2 | Medical devices having improved mechanical performance | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-20090186067-A1 | MEDICAL DEVICES HAVING IMPROVED MECHANICAL PERFORMANCE | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-20080051542-A1 | Medical devices having polymeric regions with improved adhesion | STRICKLER FREDERICK H | 2008-02-28 | — | — | US | disclosed |
| US-20080051541-A1 | Medical devices having improved mechanical performance | BOSTON SCIENTIFIC SCIMED, INC. | 2008-02-28 | — | — | US | disclosed |