SCHEMBL10042852

SCHEMBL10042852

COc1cccc(N(C)c2ccc(-c3ccc(N(c4ccc(C)cc4)c4cccc(OC)c4)cc3)cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 6/20 0.52
MTNR1B P49286 6/20 0.52
HSD17B2 P37059 6/20 0.44
HSD17B1 P14061 5/20 0.44
ADRA2A P08913 2/20 0.43
ADRA1A P35348 2/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
ADRA1D P25100 1/20 0.43
ADRA1B P35368 1/20 0.43
ACHE P22303 1/20 0.42
ALKBH3 Q96Q83 1/20 0.41
MAOB P27338 1/20 0.40
KDM4C Q9H3R0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12048242 0.94 MTNR1A (0.56) MTNR1AMTNR1BHSD17B2HSD17B1ADRA2A
SCHEMBL10042868 0.93 MTNR1A (0.51) MTNR1AMTNR1BHSD17B2HSD17B1ACHE
SCHEMBL13929902 0.93 ACHE (0.48) MTNR1AMTNR1BHSD17B2HSD17B1ADRA2A
SCHEMBL18052478 0.93 ACHE (0.48) MTNR1AMTNR1BHSD17B2HSD17B1ADRA2A
SCHEMBL9581416 0.93 ACHE (0.48) MTNR1AMTNR1BHSD17B2HSD17B1ADRA2A
SCHEMBL12048224 0.91 MTNR1A (0.54) MTNR1AMTNR1BHSD17B2HSD17B1ADRA2A
SCHEMBL12048278 0.90 MTNR1A (0.55) MTNR1AMTNR1BHSD17B2HSD17B1
SCHEMBL22166438 0.89 MTNR1A (0.60) MTNR1AMTNR1BHSD17B2HSD17B1ADRA2A
SCHEMBL12048140 0.88 MTNR1A (0.53) MTNR1AMTNR1BHSD17B2HSD17B1
SCHEMBL12048630 0.88 MTNR1A (0.53) MTNR1AMTNR1BHSD17B2HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9972802-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2018-05-15 US disclosed
US-9773993-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2017-09-26 US disclosed
US-9640775-B2 Organic electroluminescence element Konica Minolta, Inc. (JP) 2017-05-02 US disclosed
US-20160336526-A1 ELECTROLUMINESCENCE ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-11-17 US disclosed
US-9257651-B2 Organic electroluminescence element and method for manufacturing organic electroluminescence element KONICA MINOLTA HOLDINGS, INC. (JP) 2016-02-09 US disclosed
US-20150076469-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-03-19 US disclosed
US-8980443-B2 Organic electroluminescent element KONICA MINOLTA HOLDINGS, INC. (JP) 2015-03-17 US disclosed
US-8759826-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2014-06-24 US disclosed
US-20130200360-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KONICA MINOLTA , INC. (JP) 2013-08-08 US disclosed
US-20130087778-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENCE ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-11 US disclosed
US-20120037889-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND ILLUMINATION DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-02-16 US disclosed
US-20120007072-A1 ORGANIC ELECTROLUMINESCENT ELEMENT MERCK PATENT GMBH (DE) 2012-01-12 US disclosed