SCHEMBL10042875

SCHEMBL10042875

Cc1ccc(N(C)c2ccc(Oc3ccc(N(c4ccc(C)cc4)c4cccc(C)c4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 3/20 0.56
HSD17B2 P37059 3/20 0.56
TDP1 Q9NUW8 3/20 0.44
HTT P42858 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KDM4C Q9H3R0 2/20 0.44
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.39
NR1I2 O75469 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTR2B P41595 1/20 0.39
CYP51A1 Q16850 1/20 0.39
TEAD4 Q15561 1/20 0.38
POLB P06746 1/20 0.37
HTR2A P28223 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13030516 0.94 HSD17B1 (0.57) HSD17B1HSD17B2TDP1HTTL3MBTL1
SCHEMBL12700501 0.90 HSD17B1 (0.42) HSD17B1HSD17B2TDP1KDM4CALDH1A1
SCHEMBL8943708 0.90 HSD17B1 (0.53) HSD17B1HSD17B2TDP1HTTL3MBTL1
SCHEMBL10042869 0.90 HSD17B1 (0.42) HSD17B1HSD17B2TDP1KDM4CALDH1A1
SCHEMBL10042837 0.89 CSF1R (0.41) HSD17B1HSD17B2TDP1KDM4CALDH1A1
SCHEMBL8943824 0.87 HSD17B1 (0.50) HSD17B1HSD17B2TDP1HTTL3MBTL1
SCHEMBL10042880 0.87 HTT (0.46) HSD17B1HSD17B2TDP1HTTL3MBTL1
SCHEMBL12048248 0.87 CSF1R (0.42) HSD17B1HSD17B2TDP1KDM4CALDH1A1
SCHEMBL10042849 0.86 ACHE (0.47) HSD17B1HSD17B2TDP1KDM4CMAPT
SCHEMBL10042856 0.85 HSD17B1 (0.44) HSD17B1HSD17B2TDP1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9972802-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2018-05-15 US disclosed
US-9773993-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2017-09-26 US disclosed
US-9640775-B2 Organic electroluminescence element Konica Minolta, Inc. (JP) 2017-05-02 US disclosed
US-20160336526-A1 ELECTROLUMINESCENCE ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-11-17 US disclosed
US-9257651-B2 Organic electroluminescence element and method for manufacturing organic electroluminescence element KONICA MINOLTA HOLDINGS, INC. (JP) 2016-02-09 US disclosed
US-20150076469-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-03-19 US disclosed
US-8980443-B2 Organic electroluminescent element KONICA MINOLTA HOLDINGS, INC. (JP) 2015-03-17 US disclosed
US-8759826-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2014-06-24 US disclosed
US-20130200360-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KONICA MINOLTA , INC. (JP) 2013-08-08 US disclosed
US-20130087778-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENCE ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-11 US disclosed
US-20120037889-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND ILLUMINATION DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-02-16 US disclosed
US-20120007072-A1 ORGANIC ELECTROLUMINESCENT ELEMENT MERCK PATENT GMBH (DE) 2012-01-12 US disclosed