SCHEMBL10044110

SCHEMBL10044110

CCC(C)C(O)C(=O)NCCc1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.55
F13A1 P00488 1/20 0.55
CTSL P07711 1/20 0.52
CTSB P07858 1/20 0.52
HTT P42858 1/20 0.51
ESRRG P62508 5/20 0.49
ESRRB O95718 3/20 0.49
GAA P10253 1/20 0.49
GLI1 P08151 1/20 0.48
GLI2 P10070 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA14 Q9ULX7 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
POLB P06746 1/20 0.47
ADRB2 P07550 2/20 0.46
LMNA P02545 2/20 0.46
SLC6A2 P23975 2/20 0.46
SLC6A4 P31645 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10448164 0.84 KDM4E (0.54) KDM4EF13A1CTSLCTSBHTT
SCHEMBL18324609 0.83 GAA (0.68) KDM4EF13A1CTSLCTSBHTT
SCHEMBL29655176 0.83 KDM4E (0.64) KDM4EF13A1ESRRGESRRBGAA
SCHEMBL5060920 0.83 KDM4E (0.64) KDM4EF13A1ESRRGESRRBGAA
SCHEMBL4949918 0.83 KDM4E (0.64) KDM4EF13A1ESRRGESRRBGAA
SCHEMBL12164125 0.81 KDM4E (0.66) KDM4EF13A1ESRRGESRRBGAA
SCHEMBL22365531 0.80 ESRRG (0.50) KDM4EF13A1CTSLCTSBHTT
SCHEMBL27183242 0.79 KDM4E (0.54) KDM4EF13A1ESRRGESRRBGAA
SCHEMBL30873100 0.79 KDM4E (0.54) KDM4EF13A1ESRRGESRRBGAA
SCHEMBL11135700 0.78 KDM4E (0.62) KDM4EF13A1ESRRGESRRBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015081390-A2 METHOD FOR CONTROLLING ANT COLONIES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2015-06-11 WO claimed
US-11767289-B2 Methods and compositions for pest control UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2023-09-26 US disclosed
US-11767289-B2 Methods and compositions for pest control UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2023-09-26 US disclosed
US-20220234997-A1 Methods and Compositions for Pest Control THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2022-07-28 US disclosed
US-9950994-B2 Methods and compositions for pest control VMI FOUNDATION (US) 2018-04-24 US disclosed
US-9950994-B2 Methods and compositions for pest control VMI FOUNDATION (US) 2018-04-24 US disclosed
US-20180009740-A1 Methods and Compositions for Pest Control THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2018-01-11 US disclosed
WO-2015081390-A2 METHOD FOR CONTROLLING ANT COLONIES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2015-06-11 WO disclosed
US-20130289125-A1 Methods and Compositions for Pest Control THE VMI FOUNDATION 2013-10-31 US disclosed
US-20130289125-A1 Methods and Compositions for Pest Control THE VMI FOUNDATION 2013-10-31 US disclosed
WO-2012061624-A2 Methods and Compositions for Pest Control VMI FOUNDATION (US) 2012-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767289-B2 Methods and compositions for pest control TYR, GLMN, SGMS2 KDM4E 424/4885F13A1 3867/4885CTSL 1565/4885
US-20130289125-A1 Methods and Compositions for Pest Control TYR, GLMN, SGMS2 KDM4E 424/4885F13A1 3867/4885CTSL 1565/4885
US-20180009740-A1 Methods and Compositions for Pest Control TYR, GLMN, SGMS2 KDM4E 424/4885F13A1 3867/4885CTSL 1565/4885
US-20220234997-A1 Methods and Compositions for Pest Control TYR, GLMN, SGMS2 KDM4E 424/4885F13A1 3867/4885CTSL 1565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.