Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | F13A1 | P00488 | 1/20 | 0.64 |
| ▸ | ESRRG | P62508 | 3/20 | 0.55 |
| ▸ | ESRRB | O95718 | 2/20 | 0.55 |
| ▸ | GLI1 | P08151 | 1/20 | 0.53 |
| ▸ | GLI2 | P10070 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5060920 | 1.00 | KDM4E (0.64) | KDM4EF13A1ESRRGESRRBGLI1 | |
| SCHEMBL4949918 | 1.00 | KDM4E (0.64) | KDM4EF13A1ESRRGESRRBGLI1 | |
| SCHEMBL12164125 | 0.88 | KDM4E (0.66) | KDM4EF13A1ESRRGESRRBGLI1 | |
| SCHEMBL11135700 | 0.85 | KDM4E (0.62) | KDM4EF13A1ESRRGESRRBGLI1 | |
| SCHEMBL31126659 | 0.84 | KMT2A (0.63) | CYP2D6NPC1MAPTCYP2C19RAB9A | |
| SCHEMBL2733102 | 0.84 | KDM4E (0.57) | KDM4EF13A1ESRRGESRRBGLI1 | |
| SCHEMBL18324609 | 0.83 | GAA (0.68) | KDM4EF13A1ESRRGESRRBGLI1 | |
| Hydrochloric Acid SCHEMBL11140134 | 0.83 | KDM4E (0.60) | KDM4EF13A1ESRRGESRRBGLI1 | |
| SCHEMBL10044110 | 0.83 | KDM4E (0.55) | KDM4EF13A1ESRRGESRRBGLI1 | |
| SCHEMBL4948472 | 0.82 | ERCC1 (0.51) | KDM4EF13A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | KDM4E 3699/4885F13A1 3546/4885ESRRG 3018/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | KDM4E 3699/4885F13A1 3546/4885ESRRG 3018/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | KDM4E 3699/4885F13A1 3546/4885ESRRG 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.