⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23529597 | 0.97 | — | — | |
| SCHEMBL6634673 | 0.85 | HDAC3 (0.63) | — | |
| SCHEMBL11027904 | 0.84 | — | — | |
| SCHEMBL11029486 | 0.82 | HSP90AA1 (0.58) | — | |
| SCHEMBL29040279 | 0.80 | HSP90AA1 (0.61) | — | |
| SCHEMBL24658011 | 0.80 | HSP90AA1 (0.61) | — | |
| SCHEMBL13568685 | 0.80 | HSP90AA1 (0.61) | — | |
| SCHEMBL24657787 | 0.80 | HSP90AA1 (0.61) | — | |
| SCHEMBL6124941 | 0.80 | KDM4E (0.64) | — | |
| SCHEMBL20392386 | 0.79 | CTSD (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279167-B | Matrine compound derivative and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2018-11-13 | — | — | CN | claimed |
| EP-3057948-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2016-08-24 | — | — | EP | claimed |
| WO-2015057655-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | claimed |
| WO-2024149345-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2024-07-18 | — | — | WO | disclosed |
| EP-4366777-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023223055-A1 | ANTI-VIRAL COMPOUNDS | Infex Therapeutics Limited (GB) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |
| EP-3873938-A1 | DC-SIGN ANTIBODY CONJUGATES COMPRISING STING AGONISTS | Novartis AG (CH) | 2021-09-08 | — | — | EP | disclosed |
| EP-3313884-B1 | ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF | IMMUNOGEN INC (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3737665-A1 | PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF | XW Laboratories Inc. (KY) | 2020-11-18 | — | — | EP | disclosed |
| CN-110062753-A | Antiviral compounds | 哈普洛根有限责任公司 | 2019-07-26 | — | — | CN | disclosed |
| US-20170158598-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-06-08 | — | — | US | disclosed |
| US-9629363-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-04-25 | — | — | US | disclosed |
| US-20160037779-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-02-11 | — | — | US | disclosed |
| US-9211281-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2015-12-15 | — | — | US | disclosed |
| US-20140171311-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-06-19 | — | — | US | disclosed |
| US-20130041178-A1 | METHOD FOR PREPARING OPTICALLY ACTIVE N-METHYLAMINO ACIDS AND OPTICALLY ACTIVE N-METHYLAMINO ACID AMIDES | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2013-02-14 | — | — | US | disclosed |
| WO-2012017971-A1 | PEST CONTROL COMPOSITION | 住友化学株式会社 (JP) | 2012-02-09 | — | — | WO | disclosed |
| US-7919623-B2 | Naphthyridine derivatives having inhibitory activity against HIV integrase | SHIONOGI & CO., LTD. (JP) | 2011-04-05 | — | — | US | disclosed |
| US-20090227621-A1 | Naphthyridine derivatives having inhibitory activity against hiv integrase | SHIONOGI & CO., LTD. (JP) | 2009-09-10 | — | — | US | disclosed |