SCHEMBL10044149

SCHEMBL10044149

CC(=O)c1ccc(Oc2ccc(Oc3ccc(C(=O)c4ccc(Oc5ccc(-c6ccc(Oc7ccccc7)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 4/20 0.66
MAPT P10636 4/20 0.66
RAB9A P51151 2/20 0.66
HPGD P15428 1/20 0.66
SMN1; SMN2 Q16637 2/20 0.63
ACACB O00763 2/20 0.59
ACACA Q13085 2/20 0.59
LMNA P02545 2/20 0.56
ALDH1A1 P00352 1/20 0.56
HTT P42858 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ELANE P08246 1/20 0.56
PARP10 Q53GL7 1/20 0.53
POLB P06746 1/20 0.51
MAOB P27338 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18656343 1.00 SRD5A2 (0.66) SRD5A2MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL18656372 1.00 SRD5A2 (0.66) SRD5A2MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL21935080 0.95 MAPT (0.73) SRD5A2MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL12240715 0.95 MAPT (0.73) SRD5A2MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL21935942 0.91 MAPT (0.73) SRD5A2MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL5478747 0.91 MAPT (0.77) SRD5A2MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL9814564 0.91 SRD5A2 (0.78) SRD5A2MAPTRAB9AACACBACACA
SCHEMBL20081140 0.91 SRD5A2 (0.78) SRD5A2MAPTRAB9AACACBACACA
SCHEMBL167640 0.89 RAB9A (0.83) SRD5A2MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL12757139 0.87 SRD5A2 (0.71) SRD5A2MAPTRAB9ASMN1; SMN2ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120165480-A1 STERILIZATION CHAMBER MADE OF A POLYMERIC MATERIAL, PROCESS FOR ITS MANUFACTURE AND STERILIZATION APPARATUS COMPRISING THIS CHAMBER SOLVAY ADVANCED POLYMERS L.L.C. (US) 2012-06-28 US disclosed