SCHEMBL10044280

SCHEMBL10044280

Cc1cccc(C)c1OI

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.43
CYP2A6 P11509 1/20 0.43
TSHR P16473 2/20 0.42
ACHE P22303 1/20 0.42
SCN4A P35499 9/20 0.41
LMNA P02545 2/20 0.41
SCN1A P35498 2/20 0.41
SCN5A Q14524 2/20 0.41
SCN9A Q15858 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
NFKB1 P19838 2/20 0.41
CYP2C9 P11712 1/20 0.41
KCNK3 O14649 1/20 0.41
CACNA1F O60840 1/20 0.41
KCNK2 O95069 1/20 0.41
GBA1 P04062 1/20 0.41
MAOA P21397 1/20 0.41
HTR2A P28223 1/20 0.41
SLC6A4 P31645 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10336028 0.76 KDM4E (0.66) CYP1A2TSHRLMNACYP3A4CYP2C9
SCHEMBL437049 0.75 HSP90AA1 (0.50) CYP1A2CYP2A6TSHRACHESCN4A
Phosphine SCHEMBL21753753 0.73 HSP90AA1 (0.48) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL145464 0.73 ALDH1A1 (0.48) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL2094083 0.72 SCN4A (0.54) CYP1A2TSHRSCN4ALMNASCN1A
SCHEMBL30686934 0.71 CYP1A2 (0.43) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL1046570 0.71 CYP1A2 (0.43) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL3288767 0.71 CYP1A2 (0.43) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL4821766 0.71 CYP1A2 (0.43) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL8403772 0.71 CYP1A2 (0.43) CYP1A2CYP2A6TSHRACHESCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012007948-A2 CYTOTOXIC Ti (IV) COMPOUNDS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2012-01-19 WO disclosed
EP-2055709-A2 Novel red electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-05-06 EP disclosed