SCHEMBL3288767

SCHEMBL3288767

Cc1cccc(C)c1OCl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.43
CYP2A6 P11509 1/20 0.43
TSHR P16473 2/20 0.42
ACHE P22303 1/20 0.42
SCN4A P35499 9/20 0.41
LMNA P02545 2/20 0.41
SCN1A P35498 2/20 0.41
SCN5A Q14524 2/20 0.41
SCN9A Q15858 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
NFKB1 P19838 2/20 0.41
CYP2C9 P11712 1/20 0.41
KCNK3 O14649 1/20 0.41
CACNA1F O60840 1/20 0.41
KCNK2 O95069 1/20 0.41
GBA1 P04062 1/20 0.41
MAOA P21397 1/20 0.41
HTR2A P28223 1/20 0.41
SLC6A4 P31645 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14985358 0.85 KDM4E (0.49) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL11678596 0.78 ALDH1A1 (0.54) CYP1A2TSHRLMNACYP2C9ALDH1A1
SCHEMBL9548012 0.77 CYP1A2 (0.43) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL437049 0.75 HSP90AA1 (0.50) CYP1A2CYP2A6TSHRACHESCN4A
Acetic Acid SCHEMBL16005821 0.75 KMT2A (0.50) CYP1A2TSHRLMNACYP2D6ALDH1A1
Phosphine SCHEMBL21753753 0.73 HSP90AA1 (0.48) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL145464 0.73 ALDH1A1 (0.48) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL30686934 0.71 CYP1A2 (0.43) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL4821766 0.71 CYP1A2 (0.43) CYP1A2CYP2A6TSHRACHESCN4A
SCHEMBL1046570 0.71 CYP1A2 (0.43) CYP1A2CYP2A6TSHRACHESCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734912-A2 HIGH SEPARATION DUAL PHASE EYE MAKE-UP REMOVER Mary Kay, Inc. (US) 2026-05-06 EP disclosed
WO-2026087386-A1 ROSIN DIESTER COMPOUNDS AND USES THEREOF FIRMENICH SA (CH) 2026-04-30 WO disclosed
US-20260090980-A1 COSMETIC COMPOSITIONS AND METHODS OF USING THE SAME MARY KAY INC. (US) 2026-04-02 US disclosed
US-20260083659-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE MARY KAY INC. (US) 2026-03-26 US disclosed
WO-2025264660-A1 COSMETIC COMPOSITION COMPRISING CAFFEINE AND MELATONIN MARY KAY INC. (US) 2025-12-26 WO disclosed
US-20250387310-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2025-12-25 US disclosed
US-20250381117-A1 COSMETIC COMPOSITION COMPRISING CAFFEINE AND MELATONIN MARY KAY INC. (US) 2025-12-18 US disclosed
WO-2025202256-A1 COOLING COMPOSITION FIRMENICH SA (CH) 2025-10-02 WO disclosed
EP-4593967-A2 COSMETIC COMPOSITIONS AND METHODS OF USING THE SAME Mary Kay, Inc. (US) 2025-08-06 EP disclosed
EP-4583718-A1 FLAVONOID COMPOSITIONS AND USES THEREOF Firmenich SA (CH) 2025-07-16 EP disclosed
EP-1889850-B1 NOVEL TRITERPENIC ACID DERIVATIVE AND PREPARATION FOR EXTERNAL APPLICATION FOR SKIN COMPRISING THE SAME POLA CHEM IND INC (JP) 2014-03-05 EP disclosed
CN-101166510-B External preparation for skin SBI ALAPROMO CO LTD 2012-03-07 CN disclosed
US-20110060042-A1 EXTERNAL PREPARATION FOR SKIN SBI ALAPROMO CO., LTD. (JP) 2011-03-10 US disclosed
US-7718635-B2 Triterpenic acid derivative and preparation for external application for skin comprising the same POLA CHEMICAL INDUSTRIES INC. (JP) 2010-05-18 US disclosed
US-20090130227-A1 EXTERNAL PREPARATION FOR SKIN SBI ALAPROMO CO., LTD. (JP) 2009-05-21 US disclosed
US-20090075946-A1 NOVEL TRITERPENIC ACID DERIVATIVE AND PREPARATION FOR EXTERNAL APPLICATION FOR SKIN COMPRISING THE SAME POLA CHEMICAL INDUSTRIES INC. (JP) 2009-03-19 US disclosed
CN-101166510-A External preparation for skin COSMO OIL CO LTD (JP) 2008-04-23 CN disclosed
EP-1889850-A1 NOVEL TRITERPENIC ACID DERIVATIVE AND PREPARATION FOR EXTERNAL APPLICATION FOR SKIN COMPRISING THE SAME Pola Chemical Industries Inc. (JP) 2008-02-20 EP disclosed
EP-1878421-A1 EXTERNAL PREPARATION FOR SKIN COSMO OIL CO., LTD (JP) 2008-01-16 EP disclosed
US-3931340-A Chlorination of aromatic compounds ASAHI DENKA KOGYO K.K. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260090980-A1 COSMETIC COMPOSITIONS AND METHODS OF USING THE SAME CUTA, DSG1, HIRA CYP1A2 706/4885CYP2A6 3463/4885TSHR 3804/4885
US-20250387310-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT TAS2R30, TAS2R1, TAS2R20 CYP1A2 1058/4885CYP2A6 515/4885TSHR 4612/4885
US-20090075946-A1 NOVEL TRITERPENIC ACID DERIVATIVE AND PREPARATION FOR EXTERNAL APPLICATION FOR SKIN COMPRISING THE SAME DUSP4, CUTA, DUSP22 CYP1A2 2457/4885CYP2A6 1608/4885TSHR 2815/4885
US-20260083659-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE CUTA, TYR, SUN2 CYP1A2 144/4885CYP2A6 1216/4885TSHR 2955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.