Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16295375 | 0.93 | TSHR (0.51) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL20214256 | 0.93 | TSHR (0.51) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10044323 | 0.93 | TSHR (0.51) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL21842558 | 0.86 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL21705279 | 0.80 | HDAC3 (0.38) | TSHRALDH1A1HSD17B10CYP3A4HDAC3 | |
| SCHEMBL24195883 | 0.79 | TSHR (0.51) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL21705281 | 0.78 | HDAC3 (0.43) | TSHRALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL6886176 | 0.78 | THRB (0.41) | TSHRALDH1A1THRBHDAC3HDAC4 | |
| SCHEMBL21705759 | 0.78 | HDAC3 (0.37) | TSHRALDH1A1HSD17B10CYP3A4HDAC3 | |
| SCHEMBL10044295 | 0.78 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10814042-B2 | Radiopaque polymers for medical devices | ENDOSHAPE, INC. (US) | 2020-10-27 | — | — | US | disclosed |
| EP-2953650-B1 | RADIOPAQUE POLYMERS FOR MEDICAL DEVICES | ENDOSHAPE INC (US) | 2020-09-30 | — | — | EP | disclosed |
| EP-3482776-B1 | RADIOPAQUE SHAPE MEMORY POLYMERS FOR MEDICAL DEVICES | ENDOSHAPE INC (US) | 2020-07-15 | — | — | EP | disclosed |
| US-10590218-B2 | Polymer compositions with enhanced radiopacity | ENDOSHAPE, INC. (US) | 2020-03-17 | — | — | US | disclosed |
| US-20200061252-A1 | RADIOPAQUE POLYMERS FOR MEDICAL DEVICES | EMBOLIZATION, INC. | 2020-02-27 | — | — | US | disclosed |
| US-10434223-B2 | Radiopaque polymers for medical devices | ENDOSHAPE, INC. (US) | 2019-10-08 | — | — | US | disclosed |
| EP-3482776-A1 | RADIOPAQUE SHAPE MEMORY POLYMERS FOR MEDICAL DEVICES | Endoshape, Inc. (US) | 2019-05-15 | — | — | EP | disclosed |
| EP-2968620-B1 | POLYMER COMPOSITIONS WITH ENHANCED RADIOPACITY | ENDOSHAPE INC (US) | 2019-02-13 | — | — | EP | disclosed |
| US-20180126045-A1 | RADIOPAQUE POLYMERS FOR MEDICAL DEVICES | EMBOLIZATION, INC. | 2018-05-10 | — | — | US | disclosed |
| US-20180126045-A1 | RADIOPAQUE POLYMERS FOR MEDICAL DEVICES | EMBOLIZATION, INC. | 2018-05-10 | — | — | US | disclosed |
| US-20160024239-A1 | POLYMER COMPOSITIONS WITH ENHANCED RADIOPACITY | EMBOLIZATION, INC. | 2016-01-28 | — | — | US | disclosed |
| US-20150374884-A1 | RADIOPAQUE POLYMERS FOR MEDICAL DEVICES | EMBOLIZATION, INC. | 2015-12-31 | — | — | US | disclosed |
| US-20150374884-A1 | RADIOPAQUE POLYMERS FOR MEDICAL DEVICES | EMBOLIZATION, INC. | 2015-12-31 | — | — | US | disclosed |
| US-9062141-B2 | Radiopaque shape memory polymers for medical devices | ENDOSHAPE, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-9062141-B2 | Radiopaque shape memory polymers for medical devices | ENDOSHAPE, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| WO-2014200594-A1 | POLYMER COMPOSITIONS WITH ENHANCED RADIOPACITY | ENDOSHAPE, INC. (US) | 2014-12-18 | — | — | WO | disclosed |
| WO-2014124225-A1 | RADIOPAQUE POLYMERS FOR MEDICAL DEVICES | ENDOSHAPE, INC. (US) | 2014-08-14 | — | — | WO | disclosed |
| US-20130225778-A1 | RADIOPAQUE SHAPE MEMORY POLYMERS FOR MEDICAL DEVICES | EMBOLIZATION, INC. | 2013-08-29 | — | — | US | disclosed |
| US-20130225778-A1 | RADIOPAQUE SHAPE MEMORY POLYMERS FOR MEDICAL DEVICES | EMBOLIZATION, INC. | 2013-08-29 | — | — | US | disclosed |
| WO-2012019145-A1 | RADIOPAQUE SHAPE MEMORY POLYMERS FOR MEDICAL DEVICES | ENDOSHAPE, INC. (US) | 2012-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180126045-A1 | RADIOPAQUE POLYMERS FOR MEDICAL DEVICES | PARN, MMS19, RAD50 | TSHR 2016/4885ALDH1A1 4691/4885TP53 1128/4885 |
| US-10590218-B2 | Polymer compositions with enhanced radiopacity | PARN, PARG, RAD50 | TSHR 4094/4885ALDH1A1 4687/4885TP53 230/4885 |
| US-10814042-B2 | Radiopaque polymers for medical devices | PARN, MMS19, RAD50 | TSHR 2016/4885ALDH1A1 4691/4885TP53 1128/4885 |
| US-20200061252-A1 | RADIOPAQUE POLYMERS FOR MEDICAL DEVICES | PARN, MMS19, RAD50 | TSHR 2016/4885ALDH1A1 4691/4885TP53 1128/4885 |
| US-10434223-B2 | Radiopaque polymers for medical devices | PARN, MMS19, RAD50 | TSHR 2016/4885ALDH1A1 4691/4885TP53 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.