Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12680023 | 0.93 | TSHR (0.57) | TSHRHPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL14275065 | 0.83 | HPGD (0.43) | TSHRHPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL10044365 | 0.81 | SMN1; SMN2 (0.85) | TSHRHPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL12417188 | 0.77 | TSHR (0.54) | TSHRHPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL10889100 | 0.77 | SMN1; SMN2 (0.42) | HPGDHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL17948493 | 0.76 | NAMPT (0.38) | TSHRHPGDHTTSMN1; SMN2KMT2A | |
| SCHEMBL12013650 | 0.75 | TSHR (0.88) | TSHRHPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL4270085 | 0.75 | TSHR (0.88) | TSHRHPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL8574782 | 0.75 | TSHR (0.88) | TSHRHPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL12013653 | 0.75 | TSHR (0.88) | TSHRHPGDHTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9005985-B2 | Optical reporter compositions | APDN (B.V.I.) INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20130149706-A1 | OPTICAL REPORTER COMPOSITIONS | APDN (B.V.I.) Inc., dba Applied DNA Sciences, Inc. (US) | 2013-06-13 | — | — | US | disclosed |
| US-8426216-B2 | Methods for authenticating articles with optical reporters | APDN (B.V.I.), Inc. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8420400-B2 | System and method for authenticating tablets | APDN (B.V.I.), Inc. (US) | 2013-04-16 | — | — | US | disclosed |
| US-8415165-B2 | System and method for authenticating sports identification goods | APDN (B.V.I.), Inc. (US) | 2013-04-09 | — | — | US | disclosed |
| US-20120252025-A1 | METHODS FOR COVALENT LINKING OF OPTICAL REPORTERS | APDN, Inc. | 2012-10-04 | — | — | US | disclosed |
| US-8124333-B2 | Methods for covalent linking of optical reporters | APDN, Inc. (VG) | 2012-02-28 | — | — | US | disclosed |
| US-20090075261-A1 | SYSTEM AND METHOD FOR AUTHENTICATING TABLETS | APDN (B.V.I.) INC. (VG) | 2009-03-19 | — | — | US | disclosed |
| US-20090042191-A1 | SYSTEM AND METHOD FOR SECURE DOCUMENT PRINTING AND DETECTION | APDN (B.V.I.) INC. | 2009-02-12 | — | — | US | disclosed |
| US-20090042191-A1 | SYSTEM AND METHOD FOR SECURE DOCUMENT PRINTING AND DETECTION | APDN (B.V.I.) INC. | 2009-02-12 | — | — | US | disclosed |
| US-20080312427-A1 | METHODS FOR COVALENT LINKING OF OPTICAL REPORTERS | APDN (B.V.I.) INC. | 2008-12-18 | — | — | US | disclosed |
| US-20080299559-A1 | METHODS FOR AUTHENTICATING ARTICLES WITH OPTICAL REPORTERS | APDN (B.V.I.) INC. | 2008-12-04 | — | — | US | disclosed |
| US-20080293052-A1 | SYSTEM AND METHOD FOR AUTHENTICATING SPORTS IDENTIFICATION GOODS | APDN (B.V.I.) INC. | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312427-A1 | METHODS FOR COVALENT LINKING OF OPTICAL REPORTERS | PCNA, POLL, LIG3 | TSHR 3495/4885HPGD 3824/4885HTT 1153/4885 |
| US-20120252025-A1 | METHODS FOR COVALENT LINKING OF OPTICAL REPORTERS | PCNA, POLL, LIG3 | TSHR 3495/4885HPGD 3824/4885HTT 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.