Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14275065 | 0.89 | HPGD (0.43) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL20821713 | 0.83 | HPGD (0.43) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL19432778 | 0.79 | CYP2D6 (0.35) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL16203504 | 0.79 | LMNA (0.39) | LMNAPOLB | |
| SCHEMBL22729318 | 0.78 | TSHR (0.50) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL21162206 | 0.78 | HPGD (0.39) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL12680023 | 0.78 | TSHR (0.57) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL8178094 | 0.77 | CES1 (0.43) | SMN1; SMN2LMNAKMT2APOLB | |
| SCHEMBL10044366 | 0.77 | TSHR (0.64) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL29366012 | 0.76 | LMNA (0.40) | SMN1; SMN2HPGDHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608420-A | SELF-CURING OR CURING AGENTS FOR HYDROXY COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-08-26 | — | — | US | disclosed |