Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.88 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574782 | 1.00 | TSHR (0.88) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL12013653 | 1.00 | TSHR (0.88) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL12013650 | 1.00 | TSHR (0.88) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL16581313 | 0.93 | TSHR (0.76) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL13483554 | 0.93 | TSHR (0.76) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL12733524 | 0.93 | TSHR (0.76) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL13431136 | 0.93 | TSHR (0.76) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL12297359 | 0.93 | TSHR (0.76) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL13656030 | 0.93 | TSHR (0.76) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL14421970 | 0.93 | TSHR (0.76) | TSHRHPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456412-B1 | COMPOSITION AND METHOD FOR COLOURING HAIR | KAO GERMANY GMBH (DE) | 2021-09-08 | — | — | EP | disclosed |
| EP-2346484-B1 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KAO GERMANY GMBH (DE) | 2019-11-06 | — | — | EP | disclosed |
| US-10238588-B2 | Aqueous oxidizing composition for hair | KAO GERMANY GMBH (DE) | 2019-03-26 | — | — | US | disclosed |
| EP-2670381-B1 | BLEACHING COMPOSITION | KAO GERMANY GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| EP-2509567-B1 | PROCESS FOR OXIDATIVE COLOURING KERATIN FIBRES | KAO GERMANY GMBH (DE) | 2017-10-04 | — | — | EP | disclosed |
| US-9776021-B2 | Anhydrous dyeing composition and process for dyeing hair | KAO GERMANY GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| US-9737475-B2 | Anhydrous dyeing composition and process for dyeing hair | KAO GERMANY GMBH (DE) | 2017-08-22 | — | — | US | disclosed |
| EP-2151233-B1 | TWO-COMPONENT OXIDATIVE HAIR DYE COMPOSITION | KAO CORP (JP) | 2017-08-09 | — | — | EP | disclosed |
| EP-2547315-B1 | COLOURING COMPOSITION FOR KERATIN FIBRES | KAO GERMANY GMBH (DE) | 2017-07-05 | — | — | EP | disclosed |
| US-9662289-B2 | Process for permanent shaping of human hair | KAO GERMANY GMBH (DE) | 2017-05-30 | — | — | US | disclosed |
| US-20090047231-A1 | AQUEOUS HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20090047231-A1 | AQUEOUS HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20080299063-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2008-12-04 | — | — | US | disclosed |
| US-20080299063-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2008-12-04 | — | — | US | disclosed |
| US-7419656-B2 | Mixture containing phenylenediamine compound | KAO CORPORATION (JP) | 2008-09-02 | — | — | US | disclosed |
| US-7419656-B2 | Mixture containing phenylenediamine compound | KAO CORPORATION (JP) | 2008-09-02 | — | — | US | disclosed |
| EP-1468666-B1 | Hair shampoo composition | KAO CORP (JP) | 2008-06-11 | — | — | EP | disclosed |
| US-7351716-B2 | Dermatological preparations | KAO CORPORATION (JP) | 2008-04-01 | — | — | US | disclosed |
| US-7351716-B2 | Dermatological preparations | KAO CORPORATION (JP) | 2008-04-01 | — | — | US | disclosed |
| EP-1362574-B1 | Method of treating hair | KAO CORP (JP) | 2007-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299063-A1 | HAIR COSMETIC COMPOSITION | H1-0, H1-3, H1-2 | TSHR 807/4885HPGD 2551/4885MEN1 314/4885 |
| US-20090047231-A1 | AQUEOUS HAIR COSMETIC COMPOSITION | POLR1C, CUTA, POLH | TSHR 794/4885HPGD 3204/4885MEN1 1367/4885 |
| US-10238588-B2 | Aqueous oxidizing composition for hair | POLR1C, GPX4, COXFA4 | TSHR 3526/4885HPGD 691/4885MEN1 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.