Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 14/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284311 | 0.91 | PIK3CG (0.56) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4286067 | 0.85 | PIK3CD (0.63) | PIK3CGPIK3CD | |
| SCHEMBL4286070 | 0.84 | PIK3CG (0.60) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4296725 | 0.83 | MAPT (0.57) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4291916 | 0.83 | PIK3CG (0.42) | MAPTPIK3CGPIK3CD | |
| SCHEMBL10044540 | 0.80 | PIK3CD (0.61) | PIK3CGPIK3CD | |
| SCHEMBL4291799 | 0.77 | PIK3CG (0.53) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4296074 | 0.74 | PIK3CG (0.70) | MAPTPIK3CGPIK3CD | |
| SCHEMBL15180089 | 0.73 | PIK3CG (0.62) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL6996405 | 0.72 | PIK3CD (0.83) | MAPTPIK3CGPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052420-A1 | METHOD FOR PREPARING SUBSTITUTED N-(3-AMINO-QUINOXALIN-2-YL)-SULFONAMIDES AND THEIR INTERMEDIATES N-(3-CHLORO-QUINOXALIN-2-YL)SULFONAMIDES | MERCK SERONO S.A. GENEVA (CH) | 2012-04-26 | — | — | WO | disclosed |