Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 19/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296074 | 0.89 | PIK3CG (0.70) | PIK3CGMAPTPIK3CD | |
| SCHEMBL4296725 | 0.89 | MAPT (0.57) | PIK3CGMAPTPIK3CDPIK3CAPIK3CB | |
| SCHEMBL10044539 | 0.84 | MAPT (0.51) | PIK3CGMAPTPIK3CDPIK3CAPIK3CB | |
| SCHEMBL18167161 | 0.83 | PIK3CG (0.47) | PIK3CGMAPT | |
| SCHEMBL4294206 | 0.83 | PIK3CG (0.54) | PIK3CGMAPTPIK3CD | |
| SCHEMBL10044925 | 0.82 | PIK3CG (0.73) | PIK3CGPIK3CD | |
| SCHEMBL15200327 | 0.81 | PIK3CG (0.67) | PIK3CGMAPTPIK3CD | |
| SCHEMBL18167160 | 0.79 | PIK3CG (0.46) | PIK3CGMAPT | |
| SCHEMBL4300600 | 0.79 | MAPT (0.54) | PIK3CGMAPTPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4296830 | 0.79 | PIK3CG (0.54) | PIK3CGMAPTPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052420-A1 | METHOD FOR PREPARING SUBSTITUTED N-(3-AMINO-QUINOXALIN-2-YL)-SULFONAMIDES AND THEIR INTERMEDIATES N-(3-CHLORO-QUINOXALIN-2-YL)SULFONAMIDES | MERCK SERONO S.A. GENEVA (CH) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012052102-A1 | QUINOXALINE DERIVATES | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |