Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227210 | 1.00 | PPARG (0.50) | PPARGMAPTCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL128035 | 0.79 | PPARG (0.48) | PPARGMAPTCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL892009 | 0.79 | PPARG (0.48) | PPARGMAPTCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL150983 | 0.79 | PPARG (0.48) | PPARGMAPTCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL11580321 | 0.78 | ALDH1A1 (0.52) | PPARGMAPTCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL11580318 | 0.78 | ALDH1A1 (0.52) | PPARGMAPTCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL2540034 | 0.78 | PPARG (0.64) | PPARGMAPTCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL176452 | 0.78 | PPARG (0.64) | PPARGMAPTCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL176453 | 0.78 | PPARG (0.64) | PPARGMAPTCYP19A1FFAR1ALDH1A1 | |
| SCHEMBL21140906 | 0.77 | PPARA (0.44) | PPARGALDH1A1PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778645-B2 | Method for the production of glutaconate | BASF SE (DE) | 2014-07-15 | — | — | US | disclosed |
| US-20120021472-A1 | Method for the Production of Glutaconate | BASF SE (DE) | 2012-01-26 | — | — | US | disclosed |