SCHEMBL10045649

SCHEMBL10045649

CN1N=C(C(=O)N=O)CCC1=O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.43
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.35
RECQL P46063 2/20 0.35
PKM P14618 2/20 0.35
GFER P55789 1/20 0.34
NPC1 O15118 2/20 0.34
POLB P06746 1/20 0.34
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
THRB P10828 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15255354 0.81
SCHEMBL2285778 0.79 RAB9A (0.47) RAB9AALDH1A1MAPTSMN1; SMN2RECQL
SCHEMBL12646078 0.79 RAB9A (0.47) RAB9AALDH1A1MAPTSMN1; SMN2RECQL
Medazomide SCHEMBL1817436 0.77 RAB9A (0.46) RAB9AALDH1A1MAPTSMN1; SMN2RECQL
SCHEMBL29442778 0.74 RAB9A (0.47) RAB9AALDH1A1MAPTSMN1; SMN2RECQL
SCHEMBL21395238 0.73 RAB9A (0.42) RAB9AALDH1A1MAPTSMN1; SMN2RECQL
SCHEMBL21394954 0.73 RAB9A (0.52) RAB9AALDH1A1MAPTSMN1; SMN2RECQL
SCHEMBL21395281 0.73 RAB9A (0.52) RAB9AALDH1A1MAPTSMN1; SMN2RECQL
SCHEMBL21395117 0.70 RAB9A (0.50) RAB9AALDH1A1MAPTSMN1; SMN2RECQL
SCHEMBL21395265 0.70 RAB9A (0.50) RAB9AALDH1A1MAPTSMN1; SMN2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8535430-B2 Hydrazine filtration method and system NEW MEXICO HIGHLANDS UNIVERSITY (US) 2013-09-17 US disclosed
US-8097074-B2 Air filtration and absorption method and system for the remediation of hydrazine NEW MEXICO HIGHLANDS UNIVERSITY (US) 2012-01-17 US disclosed
US-20110194988-A1 HYDRAZINE SPILL PAD APPARATUS AND METHOD OF MANUFACTURING NEW MEXICO HIGHLANDS UNIVERSITY 2011-08-11 US disclosed
US-20110182780-A1 HYDRAZINE FILTRATION METHOD AND SYSTEM NEW MEXICO HIGHLANDS UNIVERSITY 2011-07-28 US disclosed
US-20110011266-A1 AIR FILTRATION AND ABSORPTION METHOD AND SYSTEM FOR THE REMEDIATION OF HYDRAZINE NEW MEXICO HIGHLANDS UNIVERSITY 2011-01-20 US disclosed