Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395281 | 0.82 | RAB9A (0.52) | RAB9AALDH1A1MAPTGFERSMN1; SMN2 | |
| SCHEMBL21395265 | 0.79 | RAB9A (0.50) | RAB9AALDH1A1MAPTGFERSMN1; SMN2 | |
| SCHEMBL21395117 | 0.79 | RAB9A (0.50) | RAB9AALDH1A1MAPTGFERSMN1; SMN2 | |
| SCHEMBL12646078 | 0.77 | RAB9A (0.47) | RAB9AALDH1A1MAPTGFERSMN1; SMN2 | |
| SCHEMBL2285778 | 0.77 | RAB9A (0.47) | RAB9AALDH1A1MAPTGFERSMN1; SMN2 | |
| SCHEMBL29442778 | 0.76 | RAB9A (0.47) | RAB9AALDH1A1MAPTGFERSMN1; SMN2 | |
| Medazomide SCHEMBL1817436 | 0.76 | RAB9A (0.46) | RAB9AALDH1A1MAPTGFERSMN1; SMN2 | |
| SCHEMBL10045649 | 0.73 | RAB9A (0.43) | RAB9AALDH1A1MAPTGFERSMN1; SMN2 | |
| SCHEMBL21394830 | 0.73 | RAB9A (0.53) | RAB9AALDH1A1MAPTGFERSMN1; SMN2 | |
| SCHEMBL29359383 | 0.73 | RAB9A (0.53) | RAB9AALDH1A1MAPTGFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |