Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800983 | 0.77 | TNF (0.33) | — | |
| SCHEMBL10045808 | 0.70 | TAAR1 (0.47) | CES1FAAHKMT2ATAAR1NCEH1 | |
| SCHEMBL20805437 | 0.64 | TDP1 (0.49) | ALDH1A1TSHRRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL22946291 | 0.63 | TDP1 (0.61) | ALDH1A1TSHRPOLBKMT2ALMNA | |
| SCHEMBL17485944 | 0.60 | CYP1A2 (0.56) | ALDH1A1TSHRKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL1244820 | 0.60 | TDP1 (0.57) | ALDH1A1TSHRKDM4EKMT2ALMNA | |
| Dipicolinic Acid SCHEMBL5611142 | 0.60 | TDP1 (0.57) | ALDH1A1TSHRKDM4EKMT2ALMNA | |
| SCHEMBL29030257 | 0.59 | TDP1 (0.55) | ALDH1A1TSHRKDM4EKMT2ALMNA | |
| SCHEMBL20083642 | 0.59 | TDP1 (0.54) | ALDH1A1POLBKMT2ALMNAMAPT | |
| SCHEMBL7419155 | 0.58 | SLC1A1 (0.60) | ALDH1A1TSHRMEN1KMT2ASLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093235-B2 | Macrocyclic compounds which stabilize G-Quadruplex DNA and RNA | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-01-10 | — | — | US | disclosed |
| US-20090156627-A1 | THERAPEUTIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156627-A1 | THERAPEUTIC COMPOUNDS | TOP2B, DDB1, RECQL | CES1 4399/4885FAAH 4878/4885ALDH1A1 2075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.