Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 13/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046413 | 1.00 | EPHX1 (0.59) | EPHX1EPHX2CASP2 | |
| SCHEMBL13063728 | 0.93 | EPHX1 (0.51) | EPHX1EPHX2CASP2 | |
| SCHEMBL13063698 | 0.85 | CASP2 (0.56) | EPHX1EPHX2CASP2 | |
| SCHEMBL13827121 | 0.85 | GBA1 (0.33) | EPHX1 | |
| SCHEMBL16473143 | 0.84 | EPHX1 (0.44) | EPHX1EPHX2 | |
| SCHEMBL21243822 | 0.78 | EPHX1 (0.55) | EPHX1EPHX2CASP2 | |
| SCHEMBL25278283 | 0.77 | EPHX1 (1.00) | EPHX1EPHX2CASP2 | |
| SCHEMBL25225212 | 0.77 | EPHX1 (1.00) | EPHX1EPHX2CASP2 | |
| SCHEMBL25276783 | 0.77 | EPHX1 (1.00) | EPHX1EPHX2CASP2 | |
| SCHEMBL25228721 | 0.77 | EPHX1 (1.00) | EPHX1EPHX2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009840-A1 | PARTIALLY FLUORINATED UREAS AND AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009840-A1 | PARTIALLY FLUORINATED UREAS AND AMIDES | NAF1, FBL, UMPS | EPHX1 1825/4885EPHX2 1259/4885CASP2 2584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.