Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.64 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.56 |
| ▸ | NMT1 | P30419 | 5/20 | 0.56 |
| ▸ | NMT2 | O60551 | 4/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.46 |
| ▸ | NPY1R | P25929 | 2/20 | 0.46 |
| ▸ | NPY4R | P50391 | 2/20 | 0.46 |
| ▸ | FURIN | P09958 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340084 | 1.00 | TLR2 (0.64) | TLR2SLC6A5NMT1NMT2CTSL | |
| SCHEMBL30979546 | 0.95 | TLR2 (0.58) | TLR2SLC6A5NMT1NMT2CTSL | |
| SCHEMBL30286903 | 0.94 | TLR2 (0.59) | TLR2SLC6A5NMT1NMT2CTSL | |
| SCHEMBL29458673 | 0.94 | TLR2 (0.59) | TLR2SLC6A5NMT1NMT2CTSL | |
| SCHEMBL28354912 | 0.94 | TLR2 (0.59) | TLR2SLC6A5NMT1NMT2CTSL | |
| SCHEMBL10046476 | 0.94 | TLR2 (0.70) | TLR2SLC6A5NMT1NMT2CTSL | |
| SCHEMBL31518823 | 0.92 | TLR2 (0.58) | TLR2SLC6A5NMT1NMT2CTSL | |
| SCHEMBL30340310 | 0.91 | TLR2 (0.54) | TLR2SLC6A5NMT1NMT2CTSL | |
| SCHEMBL30340165 | 0.91 | SLC6A5 (0.69) | TLR2SLC6A5NMT1NMT2CTSL | |
| SCHEMBL10046596 | 0.89 | TLR2 (0.63) | TLR2SLC6A5NMT1NMT2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115774-A1 | ANTIMICROBIAL CATIONIC LIPO-BETA-PEPTIDES | UNIVERSITY OF MANITOBA (CA) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115774-A1 | ANTIMICROBIAL CATIONIC LIPO-BETA-PEPTIDES | NGLY1, LNPEP, VIP | TLR2 462/4885SLC6A5 3268/4885NMT1 653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.