Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18412146 | 0.95 | PDK2 (0.41) | PDK2MAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL10046604 | 0.92 | PDK2 (0.41) | PDK2MAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL6512868 | 0.87 | APEX1 (0.37) | PDK2MAPTALDH1A1SMN1; SMN2AR | |
| SCHEMBL10020298 | 0.84 | ALDH1A1 (0.35) | PDK2MAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL15891887 | 0.84 | ALDH1A1 (0.35) | PDK2MAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL25133482 | 0.81 | PDK2 (0.41) | PDK2MAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL14287922 | 0.81 | PDK2 (0.41) | PDK2MAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL18412148 | 0.79 | PDK2 (0.39) | PDK2MAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL10052530 | 0.78 | PDK2 (0.44) | PDK2MAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL30177083 | 0.77 | PDK2 (0.39) | PDK2MAPTALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917913-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-11917913-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2019-09-12 | — | — | US | disclosed |
| US-10374170-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2019-08-06 | — | — | US | disclosed |
| EP-2673249-B1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2019-04-03 | — | — | EP | disclosed |
| EP-2651862-B1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-9598637-B2 | Phosphorus-containing metal complexes | MERCK PATENT GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| US-9598637-B2 | Phosphorus-containing metal complexes | MERCK PATENT GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| EP-2896627-B1 | Metals containing organic complexes | MERCK PATENT GMBH (DE) | 2016-12-21 | — | — | EP | disclosed |
| US-20160308146-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-20130261708-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20130261708-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20130253617-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130253617-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130116755-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130116755-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| WO-2012107163-A1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |
| WO-2012079678-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012038029-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012007103-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11917913-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | PDK2 741/4885MAPT 1547/4885L3MBTL1 1480/4885 |
| US-10374170-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | PDK2 741/4885MAPT 1547/4885L3MBTL1 1480/4885 |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | OXGR1, OXTR, OCIAD2 | PDK2 741/4885MAPT 1547/4885L3MBTL1 1480/4885 |
| US-20160308146-A1 | SUBSTITUTED OXEPINES | OXGR1, OXTR, OCIAD2 | PDK2 741/4885MAPT 1547/4885L3MBTL1 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.