Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | RGS4 | P49798 | 1/20 | 0.35 |
| ▸ | RGS8 | P57771 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13383886 | 0.85 | ADORA2B (0.40) | ADORA2BCYP3A4HSD17B10RGS4RGS8 | |
| SCHEMBL24122404 | 0.85 | ADORA2B (0.41) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL331903 | 0.83 | PDE4A (0.47) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL19094969 | 0.81 | ADORA2B (0.47) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL21974369 | 0.75 | GSK3A (0.50) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL23020227 | 0.75 | GSK3A (0.50) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL13108310 | 0.75 | PDE4A (0.48) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL14591115 | 0.74 | ADORA2B (0.35) | ADORA2B | |
| SCHEMBL24031478 | 0.73 | RGS4 (0.54) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL24435697 | 0.72 | TP53 (0.44) | ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119759-B2 | Swellable sol-gels, methods of making, and use thereof | AQUANEX TECHNOLOGIES, LLC | 2012-02-21 | — | — | US | disclosed |